Longevity & Aging

Platelet-Rich Plasma Exosomes Reduce Joint Inflammation by Boosting Lymphatic Drainage

Researchers discovered that exosomes derived from platelet-rich plasma (PRP) can significantly reduce joint inflammation and pain in arthritis by enhancing the lymphatic system's drainage function. Using a mouse model of osteoarthritis, the study found that PRP exosomes activate specific cellular pathways in lymphatic vessels, improving their ability to clear inflammatory cells and proteins from inflamed joints. This represents a novel therapeutic approach that targets the root cause of persistent joint inflammation rather than just treating symptoms.