20 artigos
New research reveals how sulforaphane from cruciferous vegetables protects against ulcerative colitis by activating cellular defenses.
World-leading expert shares practical guidance on sulforaphane dosing, food sources, and chemoprotective effects in comprehensive Q&A.
Dr. Rhonda Patrick reveals how sulforaphane, omega-3s, vitamin D, and magnesium trigger cellular stress responses that enhance longevity.
Um mergulho profundo em nível molecular sobre a cinética de formação de AGEs, isoformas de RAGE, redes transcricionais a jusante e intervenções baseadas em evidências — para quem deseja o quadro mecanístico completo.
Um mergulho mecanicístico na arquitetura molecular da sinalização redox — da química de oxidação da cisteína ao direcionamento terapêutico de NRF2, NADPH oxidases e ROS mitocondriais no contexto do envelhecimento.
Resveratrol targets the USP36-SOD2 mitochondrial axis in gastric cancer, triggering autophagy and ferroptosis to suppress tumor growth.
Researchers find that combining Ganoderma lucidum and Sanghuangporus vaninii extracts may fight colorectal cancer through vitamin D and Wnt pathways.
Dr. Rhonda Patrick reveals which micronutrients support cellular stress responses and longevity, plus optimal dosing strategies.
Flaxseed compounds enhance PD-1 inhibitor effectiveness against breast cancer through gut bacteria modulation and immune system activation.
Scutellarin, a plant-derived compound, shows promise against ovarian cancer by inducing ferroptosis and blocking key survival pathways.
Network pharmacology and lab experiments reveal CTFs suppress hepatocellular carcinoma via apoptosis, ROS induction, and cell cycle arrest.
A natural plant flavonoid activates the Nrf2/FSP1 pathway to halt ferroptosis triggered by fumonisin B1, a common food contaminant.
3'-Hydroxypterostilbene from dietary plants demonstrated powerful anti-cancer effects in lab and animal studies.
A nanoparticle co-delivering sorafenib and an FSP1 inhibitor kills both tumor cells and immunosuppressive macrophages, reviving anti-tumor immunity.
Natural compound from saffron activates cellular cleanup to prevent heart damage from doxorubicin chemotherapy.
RSL3-induced ferroptosis degrades SHP2 via chaperone-mediated autophagy, amplifying IFN-γ/STAT1 signaling and enhancing anti-PD-1 immunotherapy efficacy.
New research reveals how resveratrol blocks pancreatic cancer progression by modifying a key cellular protein through succinylation.
Nova pesquisa revela que o FGF21 tem um papel fisiológico na redução do estresse do retículo endoplasmático, amplificando a resposta a proteínas mal dobradas por meio da sinalização de sulfeto.
Researchers identify NUF2 as a key driver of prostate cancer and discover fisetin, a natural compound, as a promising inhibitor of this oncogene.
Fired black sesame pigment improved liver health in mice by reshaping gut bacteria and reducing inflammation through the gut-liver axis.
Inhibiting the protein SIRT2 destabilizes a DNA repair guardian, floods tumors with killer T cells, and supercharges immunotherapy in preclinical models.
Selenomethionine shields rabbit livers from mycotoxin injury by activating protective cellular pathways and reducing oxidative stress.
