Lab-Grown Amygdala Organoids Reveal How Stress Hormones Rewire the Brain
Scientists built human amygdala-like brain organoids that model stress circuitry, uncovering a novel cortisol-driven mechanism tied to primate-specific gene regulation.
Cognitive performance, neuroplasticity, dementia prevention, and brain aging research
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Scientists built human amygdala-like brain organoids that model stress circuitry, uncovering a novel cortisol-driven mechanism tied to primate-specific gene regulation.
Researchers at Duke University tested a blood-based biomarker to stratify Alzheimer's patients from healthy adults, aiming to enable earlier detection.
Sarah Ann Macklin and Simon Hill explore how relentless health optimization creates anxiety, perfectionism, and a broken relationship with your own body.
Huberman explains how the brain remaps lost relationships and which science-backed tools accelerate adaptive grieving.
A chromatin-remodeling gene called SMARCAD1 controls tau levels — and switching it off could be a new therapeutic target for Alzheimer's.
A newly identified proteasome activator, PA200, clears toxic alpha-synuclein aggregates and maintains function even when standard protein-disposal systems fail.
Uma exploração mecanicista aprofundada de como a sinalização IKKβ/NF-κB hipotalâmica, a comunicação exossomal de htNSC e a desregulação hormonal multi-eixo impulsionam o envelhecimento sistêmico — além de estratégias terapêuticas de ponta.
New mouse research finds the trendy D+Q senolytic combo severely damages myelin, raising red flags for longevity self-experimenters.
A small trial found tocilizumab, an anti-inflammatory drug, cut depression remission rates better than SSRIs by targeting IL-6, not brain chemistry.
A completed Phase 1/2 pilot trial tested whether the senolytic duo D+Q penetrates the brain in early Alzheimer's disease.
A JAMA Insights review breaks down how hearing aids work, their limits, and whether OTC devices stack up against prescription options.
A landmark review reframes astrocytes as multilayered processing units that regulate synapses, circuits, and brain function at multiple spatial scales.