Cognitive performance, neuroplasticity, dementia prevention, and brain aging research
889 artigos
Researchers identify RORA as a key driver of cataract formation by triggering oxidative damage and cell aging in the lens — and find a small-molecule inhibitor that may reverse it.
Researchers built a machine learning imaging pipeline to detect cerebral microhemorrhages and tested SS-31 (elamipretide) in aged hypertensive mice.
A Phase 3 trial investigates whether the GLP-1 drug liraglutide can slow cognitive decline in T2DM patients at elevated Alzheimer's risk.
Sleep-wake patterns measured by wearables significantly predict dementia risk in 57,000+ older adults, matching the predictive power of genetic testing.
A professional oboist discovered that playing her instrument or singing completely suppressed her debilitating blepharospasm symptoms.
Researchers test a quantile-aggregation approach that may improve how Alzheimer's clinical trials detect treatment effects.
A pilot RCT tested whether a smartphone app could improve quality of life and treatment adherence in HIV-positive patients aged 60+.
A spatial proteomics platform profiled 700,000+ brain cells, identifying a microglial subset that clusters around amyloid-β plaques in Alzheimer's disease.
A new deep learning model from UCSF predicts Alzheimer's diagnosis and cognitive trajectories from one MRI scan—no expensive multimodal imaging required.
Behavioral scientist Dr. Nick Epley reveals how everyday social moments with strangers improve mental and physical health.
A Phase 1 trial examines whether Botulinum toxin in the glabella and forehead lifts mood and self-appearance satisfaction in returning Botox patients.
A surprising structural feature on axon initial segments lets excitatory synapses jump-start neuron firing and redirect brain circuit information flow.
