Oncology, cancer prevention, tumor biology, and immunotherapy relevant to longevity
635 artigos
Mergulhe fundo na maquinaria molecular da instabilidade genômica — dos estados de crise induzidos por telômeros e da remodelação epigenética em sítios de quebra às estratégias terapêuticas de ponta que visam a fidelidade do reparo de DNA no envelhecimento e no câncer.
Descubra o que é o DNA, como ameaças cotidianas como a luz solar e o estresse podem danificá-lo, e por que proteger seu código genético é o segredo para uma vida mais longa e saudável.
Zongertinib (Hernexeos) wins FDA approval for unresectable or metastatic HER2-mutant non-squamous NSCLC, expanding targeted therapy options.
A Danish cohort of 49,894 adults shows first-time seizures carry a 76-fold elevated risk of neurological cancer and double the risk of non-neurological cancers within one year.
Scientists discover that maintaining proteostasis in tumor-infiltrating lymphocytes prevents exhaustion and boosts immunotherapy outcomes.
A new imaging breakthrough reveals how immune cells target cancer with nanoscale precision, opening doors for better immunotherapy.
A new agentic AI framework autonomously generates biological concepts from pathology images, identifying prognostic and predictive cancer biomarkers without manual feature engineering.
A novel cell-labeling tool reveals how ERα+ macrophages create immune-excluded niches in bone, blocking T cells from destroying cancer.
Specific mutational signatures accumulate linearly with age in normal tissues, offering a new window into why cancer risk rises exponentially as we get older.
A clinical trial in Nature Cancer shows an AI model meaningfully boosts diagnostic accuracy for lung nodules, a critical step in early cancer detection.
A 156-patient multimodal study reveals two distinct immune microenvironments in breast cancer brain metastases that predict survival and immunotherapy response.
A new AI model spots pancreatic cancer on standard CT scans nearly 16 months before radiologists can see it — with nearly 3x their sensitivity.
