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Metabolic Health

Insulin resistance, blood sugar regulation, metabolic syndrome, and body composition

417 artigos

CGM Devices for Biohackers Ranked: What the Evidence Actually Shows
Metabolic Health

CGM Devices for Biohackers Ranked: What the Evidence Actually Shows

Expert reviews compare top CGMs for longevity use, but evidence for healthy adults remains limited. Here's what you need to know.

Revisão
23 de abr. de 2026 0
Two Gene Variants Combine to Trigger Earlier Diabetes Onset in Rare Family Study
Metabolic Health

Two Gene Variants Combine to Trigger Earlier Diabetes Onset in Rare Family Study

A Japanese family case reveals how inherited HNF1A and ABCC8 mutations act additively to accelerate early-onset diabetes beyond either variant alone.

Artigo Científico
23 de abr. de 2026 0
Fat Cell NAD Transporter SLC25A51 Drives Metabolic Aging and Obesity
Metabolic Health

Fat Cell NAD Transporter SLC25A51 Drives Metabolic Aging and Obesity

A newly identified mitochondrial NAD transporter in fat cells controls whether you develop obesity and insulin resistance as you age.

Artigo Científico
23 de abr. de 2026 0
Your Brain Tells Your Liver to Spike Blood Sugar When You're Stressed
Metabolic Health

Your Brain Tells Your Liver to Spike Blood Sugar When You're Stressed

A newly discovered amygdala–liver neural circuit drives stress hyperglycemia independently of cortisol or adrenaline — and chronic stress breaks it.

Artigo Científico
22 de abr. de 2026 0
PEMF Therapy Boosts Mitochondrial ATP Synthesis Without Affecting Uncoupled Respiration
Metabolic Health

PEMF Therapy Boosts Mitochondrial ATP Synthesis Without Affecting Uncoupled Respiration

New research reveals pulsed electromagnetic field therapy selectively enhances ATP-linked mitochondrial respiration, pointing to a specific cellular energy mechanism.

Artigo Científico
22 de abr. de 2026 0
Expert-Backed CGMs for Healthy Adults Reveal Glucose Insights With Evidence Gaps
Metabolic Health

Expert-Backed CGMs for Healthy Adults Reveal Glucose Insights With Evidence Gaps

Longevity experts endorse short CGM trials for non-diabetics, but RCT evidence remains thin. Here's what the data actually shows.

Revisão
22 de abr. de 2026 0
Steroid Hormone GPR56 Axis Shields the Liver from Ferroptosis
Metabolic Health

Steroid Hormone GPR56 Axis Shields the Liver from Ferroptosis

A steroid hormone activates receptor GPR56 to block ferroptosis, a form of iron-driven cell death linked to liver disease.

Artigo Científico
22 de abr. de 2026 0
Orforglipron Oral GLP-1 Pill Approved as Obesity Pipeline Heats Up
Metabolic Health

Orforglipron Oral GLP-1 Pill Approved as Obesity Pipeline Heats Up

The FDA reportedly approved Eli Lilly's orforglipron, a daily oral GLP-1 receptor agonist for obesity, marking a potential shift from injectable weight-loss drugs.

Aprovação de Medicamento
21 de abr. de 2026 0
Your Genes Load the Gun but Lifestyle Pulls the Trigger on Type 2 Diabetes
Metabolic Health

Your Genes Load the Gun but Lifestyle Pulls the Trigger on Type 2 Diabetes

A large Japanese cohort study shows polygenic risk scores predict T2D onset, yet exercise and metabolic health blunt even high genetic risk.

Artigo Científico
20 de abr. de 2026 0
CGMs for Healthy Adults Get Expert Backing but Evidence Gaps Remain
Metabolic Health

CGMs for Healthy Adults Get Expert Backing but Evidence Gaps Remain

Longevity experts endorse CGMs for metabolic optimization, but RCT evidence in non-diabetics is still thin.

Revisão
20 de abr. de 2026 0
Brain Gene FTO Drives Obesity by Hijacking Appetite Neuron Cargo Delivery
Metabolic Health

Brain Gene FTO Drives Obesity by Hijacking Appetite Neuron Cargo Delivery

FTO demethylase in AgRP neurons alters Kif1a splicing to boost neuropeptide release, promoting weight gain in mice.

Artigo Científico
19 de abr. de 2026 0
Family Metabolic Environment Shapes Children's Fatty Liver Disease Risk Beyond Womb
Metabolic Health

Family Metabolic Environment Shapes Children's Fatty Liver Disease Risk Beyond Womb

New research argues shared household metabolic factors — not just intrauterine exposure — drive MASLD risk in offspring.

Artigo Científico
19 de abr. de 2026 0
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