Stem cells, exosomes, gene therapy, peptides, hyperbaric oxygen, and epigenetic reprogramming
390 artigos
Scientists converted fibroblasts into functional osteoblasts using small molecules, then formed transplantable spheroids that repair bone defects without scaffolding.
Radiation triggers a Ca²⁺-NFATc1-Fis1 cascade that fragments mitochondria in bone marrow stem cells, halting bone repair — and silencing Fis1 reverses it.
New wearable and non-invasive glucose monitors are transforming diabetes care — here's what's available and how they work.
Researchers used prime editing to introduce and then correct a de novo GDF11 nonsense mutation, revealing Golgi stress and broad transcriptomic dysregulation.
Amgen expands late-stage testing of its long-acting obesity drug MariTide, including a trial for patients switching from rival GLP-1 medications.
A comprehensive 2025 review maps the mechanisms, sources, and clinical applications of mesenchymal stem cells and their derived exosomes across cardiovascular, neurological, autoimmune, and musculoskeletal diseases.
Mergulhe fundo em reprogramação parcial, remodelação de nicho, senolíticos e terapias clínicas de ponta — o kit de ferramentas molecular para reverter o envelhecimento das células-tronco.
Descubra o que são células-tronco, os diferentes tipos encontrados no seu corpo e por que elas são essenciais para manter seus órgãos saudáveis conforme você envelhece.
Domine os alvos moleculares de ponta, os dados de ensaios clínicos e as estratégias terapêuticas emergentes voltadas para a reversão do envelhecimento da MEC — de combinações senolíticas a scaffolds de biomateriais e reprogramação epigenética.
A redesigned CRISPR system targets the chromosomal root cause of Down syndrome, opening new doors for genetic disease intervention.
Epicrispr's GEMS platform silences disease genes epigenetically — reversibly and safely — with a single viral vector, targeting FSHD and beyond.
Researchers at MIT outline strategies to precisely control the type and strength of immune responses triggered by mRNA vaccines.
