Alzheimer's disease research, amyloid plaques, tau tangles, and cognitive decline
370 artigos
A 4-protein panel in neuronal extracellular vesicles outperforms standard plasma tests in flagging early Alzheimer's brain changes.
A comprehensive review examines how marine-derived bioactives like omega-3s, astaxanthin, and polysaccharides may combat chronic neuroinflammation underlying major neurodegenerative diseases.
Penn State researchers found abdominal contractions create pressure waves that gently rock the brain, boosting cerebrospinal fluid flow and waste clearance.
Raising Sox9 levels in aging astrocytes reduced amyloid plaque buildup and protected memory in mouse models with existing Alzheimer's symptoms.
A meta-analysis of 684,493 patients finds just 49% persist with anti-dementia drugs at 12 months, with major variation by drug type and study methodology.
A multi-cohort study finds that every 5 km closer to a lead-releasing facility is tied to measurably lower episodic memory scores.
Mergulhe na maquinaria molecular por trás da saúde cerebral ao longo da vida — das cascatas de sinalização BDNF-TrkB e da neurogênese hipocampal adulta à depuração glinfática de amiloide e intervenções de ponta, incluindo senolíticos, agonistas de GLP-1 e estimulação transcraniana.
Explore o que realmente acontece dentro do seu cérebro à medida que você envelhece — desde redes de neurônios que se retraem até mudanças nos neurotransmissores — e descubra por que algumas pessoas permanecem mentalmente afiadas até os 80 anos e além.
Blocking the protein PTP1B boosted memory and cleared brain plaque in mice, with potential links to diabetes and obesity treatment.
A 2018 paper on antileukotriene therapy and tau phosphorylation in Alzheimer's mice has been retracted due to image fraud.
MethylCog, a 29-CpG blood test, indexes general cognitive ability and improves mild cognitive impairment detection beyond age and sex alone.
A 9-day intranasal insulin regimen restored working memory, recognition memory, and reduced neuroinflammation in mice engineered to mimic hippocampal aging.
