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Latest breakthroughs in cancer research, treatment, and prevention

606 artigos

PULSAR Radiation Plus IMSA101 Immunotherapy Trial in Oligoprogressive Cancers Terminated Early
Cancer Research

PULSAR Radiation Plus IMSA101 Immunotherapy Trial in Oligoprogressive Cancers Terminated Early

A Phase 2 trial combining adaptive stereotactic radiotherapy with IMSA101 and checkpoint inhibitors was halted after enrolling only 16 patients.

Ensaio Clínico
14 de mai. de 2026 0
Pfizer Terminates Phase 1 Trial of Novel Anti-PD-1/IL-15 Fusion Protein in Solid Tumors
Cancer Research

Pfizer Terminates Phase 1 Trial of Novel Anti-PD-1/IL-15 Fusion Protein in Solid Tumors

Pfizer's first-in-human trial of PF-07209960, a dual-action immunotherapy fusion protein, was terminated after enrolling 37 patients.

Ensaio Clínico
14 de mai. de 2026 0
Personalized DNA Cancer Vaccine Shows Promise Against Deadly Brain Tumors
Cancer Research

Personalized DNA Cancer Vaccine Shows Promise Against Deadly Brain Tumors

A phase 1 trial of a neoantigen DNA vaccine for glioblastoma found strong immune responses and survival rates exceeding historical benchmarks.

Artigo Científico
14 de mai. de 2026 0
Myeloid Cell Plasticity Emerges as a Key Target for Next-Gen Cancer Therapies
Cancer Research

Myeloid Cell Plasticity Emerges as a Key Target for Next-Gen Cancer Therapies

A new review reframes how myeloid cells fuel or fight tumors, pointing to plasticity — not just cell diversity — as the core therapeutic target.

Revisão
14 de mai. de 2026 0
Nivolumab Fails to Outperform Durvalumab in Stage III Lung Cancer Trial
Cancer Research

Nivolumab Fails to Outperform Durvalumab in Stage III Lung Cancer Trial

A phase 3 trial finds nivolumab-based regimens offer no survival advantage over durvalumab for unresectable stage III NSCLC.

Artigo Científico
14 de mai. de 2026 0
Enzyme AARS2 Hijacks Lactate to Drive Liver Cancer and Becomes a Drug Target
Cancer Research

Enzyme AARS2 Hijacks Lactate to Drive Liver Cancer and Becomes a Drug Target

A newly identified enzyme links lactate metabolism to liver cancer progression, and a natural compound delivered via nanoparticles shows striking anti-tumor results.

Artigo Científico
14 de mai. de 2026 0
Urine Test May Soon Track Senescent Cells in Cancer and Fibrosis
Cancer Research

Urine Test May Soon Track Senescent Cells in Cancer and Fibrosis

Cambridge scientists engineer a nanoprobe that detects therapy-induced senescence non-invasively through a simple urine colorimetric test.

Artigo Científico
14 de mai. de 2026 0
New Senolytic Drugs Force Cancer's Zombie Cells to Self-Destruct
Cancer Research

New Senolytic Drugs Force Cancer's Zombie Cells to Self-Destruct

Scientists found drugs that kill senescent 'zombie cells' by blocking their key survival protein, shrinking tumors in mice.

Comunicado de Imprensa
13 de mai. de 2026 0
FDA Approves Zenocutuzumab-zbco for Advanced Cholangiocarcinoma
Cancer Research

FDA Approves Zenocutuzumab-zbco for Advanced Cholangiocarcinoma

The FDA approved zenocutuzumab-zbco for adults with advanced, unresectable, or metastatic cholangiocarcinoma, a rare and aggressive bile duct cancer with limited treatment options.

Aprovação de Medicamento
13 de mai. de 2026 0
Amgen's PSMA Bispecific T-Cell Engager Acapatamab Tested in Advanced Prostate Cancer
Cancer Research

Amgen's PSMA Bispecific T-Cell Engager Acapatamab Tested in Advanced Prostate Cancer

Phase 1 trial of acapatamab, a PSMA-targeting bispecific T-cell engager, enrolls 212 men with metastatic castration-resistant prostate cancer.

Ensaio Clínico
13 de mai. de 2026 0
AI-Powered ECG Predicts Heart Risk Before Cancer Treatment in 31,000 Patients
Cancer Research

AI-Powered ECG Predicts Heart Risk Before Cancer Treatment in 31,000 Patients

A large retrospective study tests whether AI-enhanced ECGs can flag cardiac risk before chemotherapy, potentially protecting cancer patients from heart damage.

Ensaio Clínico
13 de mai. de 2026 0
Physical Therapy and Relaxation Techniques Boost Resilience in Older Lung Cancer Patients
Cancer Research

Physical Therapy and Relaxation Techniques Boost Resilience in Older Lung Cancer Patients

A completed pilot trial tested physical therapy and progressive muscle relaxation to preserve function and mood in older adults with advanced lung cancer.

Ensaio Clínico
12 de mai. de 2026 0
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