Type 1 and type 2 diabetes, insulin resistance, glucose metabolism, and metabolic health
266 artigos
A large real-world study finds post-transplant diabetes requiring insulin marks a high-risk metabolic phenotype with far worse graft and patient outcomes.
A new framework redefines age-related insulin resistance as a systemic collapse of metabolic resilience spanning muscle, fat, brain, and more.
Um mergulho profundo em nível molecular sobre a cinética de formação de AGEs, isoformas de RAGE, redes transcricionais a jusante e intervenções baseadas em evidências — para quem deseja o quadro mecanístico completo.
Vá além do básico e explore os mecanismos bioquímicos por trás da glicação — da cascata da reação de Maillard à sinalização RAGE e ao entrecruzamento tecidual — para entender por que os AGEs são centrais para o envelhecimento e as doenças metabólicas.
Descubra como as moléculas de açúcar danificam silenciosamente suas proteínas e células ao longo do tempo — e o que você pode fazer para desacelerar esse processo de envelhecimento sorrateiro.
FDA approval of the first T1D delay drug nearly doubled islet autoantibody testing, but critical gaps remain in screening healthy children.
A new review links feline age-related obesity to SASP-driven chronic inflammation, offering translational insights for human metabolic disease.
The triple agonist retatrutide drives deep metabolic shifts beyond weight loss, improving key biomarkers of cardiovascular and insulin health.
Diabetes drugs like empagliflozin show surprising anti-aging effects — mimicking caloric restriction and reducing senescent cell burden.
Three new NIH-funded findings tackle metabolic aging, cardiovascular risk, and a surprising hormonal brake on brain tumors.
A rigorous MRI-based study finds that repeated hypoglycemia episodes leave brain glucose transport kinetics unchanged, challenging a leading hypothesis.
A novel endoluminal device implanted in the gut improved insulin sensitivity and weight control beyond what semaglutide achieved in a pig model.
