Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1.644 artigos
Scientists identify MRAP as a key molecular driver of thymic fat replacement, linking thymosin-α1 and FoxO1 signaling to immune aging.
Dendrobium officinale extract protects aging kidneys by activating antioxidant defenses through a key cellular signaling pathway.
A deubiquitinase stabilizes a key chaperone protein to activate protective autophagy and block iron-driven cell death in spinal discs.
Scientists discover PRDM16 declines in aged organs and its loss accelerates senescence; restoring it via GSTM1 may slow organ aging.
New research reveals omega-3s activate a receptor that curbs cellular senescence and fibrosis in kidneys, pointing to a clear biological mechanism.
Sunrise Air ditches clinic wires for a chin-worn sensor that tracks sleep apnea across multiple nights at home.
Forever Healthy's AI4L framework uses adversarial AI agents to verify every claim and citation in longevity evidence reviews.
Sam Altman-backed Retro Biosciences enters clinical trials with a drug targeting Alzheimer's protein clumps, aiming to add 10 healthy years to human life.
A multi-cohort study finds HLA-DRB1*15:01 significantly reduces longevity likelihood in northern European men, possibly via Alzheimer's and immune reactivity to LDL.
Scientists identify a glycolysis-serine axis controlled by PGK1 that governs podocyte aging, offering a new therapeutic target for chronic kidney disease.
A peptide-loaded nanocomposite hydrogel disrupts the oxidation-inflammation-aging cycle driving osteoarthritis, protecting cartilage in rat models.
Scientists discover that raising cytosolic NADPH in endothelial cells—via G6PD or folic acid—reverses hallmarks of vascular aging in mice.
