Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1.644 artigos
A 1.6-million-person cohort study finds metformin neither prevents AMD development nor slows progression to advanced disease stages.
UCL scientists propose early-life damage stays hidden until aging weakens the body's defenses, triggering diseases decades later.
A 20,000-person study validates IgG glycans as aging biomarkers, with therapeutic plasma exchange reducing glycan age by 0.4 years per month.
A new global report finds longevity clinics are scaling fast but lack the standardized frameworks needed to validate their outcomes.
Scientists discover axolotls regenerate a complete thymus from scratch, revealing midkine signaling as a key early driver with implications for reversing immune aging.
A study of 4,260 health enthusiasts found delayed-release calcium-AKG was associated with measurably younger epigenetic age.
A natural flavonoid delivered via injectable hydrogel suppresses senescence pathways in tendon stem cells, dramatically improving aged tendon healing.
Researchers built a quantitative model of IgG N-glycosylation that pinpoints a key enzyme declining with age across two Croatian cohorts.
A new review reveals how protein glycosylation—a key cellular modification—fuels aging and diabetes, and how phytochemicals may intervene.
A sweeping review maps how telomerase inhibitors evolved from lab concept to approved drug, spotlighting imetelstat's landmark approval in blood cancers.
Scientists identify TRIM24 as a master regulator of ALT telomere maintenance, revealing a new epigenetic pathway cancer cells use to avoid aging.
Scientists uncover how two major mitophagy pathways are coordinated via ubiquitylation and mitochondrial import stress, with big implications for aging.
