Gut Microbes Reprogram Host DNA Through Methylation Pathways
Comprehensive review reveals how gut bacteria modify human gene expression through epigenetic mechanisms, opening new therapeutic avenues.
20 articles
Comprehensive review reveals how gut bacteria modify human gene expression through epigenetic mechanisms, opening new therapeutic avenues.
Gut microbes deploy reversible DNA methylation changes to adapt to antibiotics and fecal transplants — even beneficial Akkermansia uses this strategy.
The first 1,000 days from conception shape lifelong health risks including obesity, diabetes, and heart disease.
A novel gut microbiome metabolite chemically modifies liver proteins, impairing mitochondrial function and insulin signaling in obesity and fatty liver disease.
Researchers discover unique RNA structures in bacteria that could inspire new approaches to cellular optimization and aging.
Study reveals how gut microbiota-derived propionic acid can restore reproductive function and reverse aging effects through gut-organ communication.
A massive deep-sea genomic survey uncovers extraordinary genetic diversity and protein structures with real-world biotechnology applications.
Go beyond probiotics and fiber — explore the cutting-edge science of fecal microbiota transplantation, engineered postbiotics, and how the gut orchestrates systemic aging through immune and neural circuits.
New research shows blocking PKM2 in immune cells promotes gut healing in colitis while preventing tumor formation.
Vaginal microbiota applied to C-section newborns restores a key brain-signaling molecule on skin, improving early neurodevelopment.
A major Cell Metabolism review reveals how microbiome metabolites reprogram immune cells to drive or prevent cardiometabolic disease.
New research shows electroacupuncture improves motor function and protects brain cells in Parkinson's disease through protein regulation.
Germ-free autism model mice show improved social behavior and reduced repetitive actions, revealing gut-brain-immune connections.
Six weeks of voluntary exercise dramatically improved social behaviors in autism model rats by reshaping gut microbiota and brain chemistry.
New perspective reveals why gut microbiome discoveries struggle to translate into effective clinical treatments
Synthetic biology meets the microbiome: designer probiotics restore gut-liver-brain balance better than rifaximin in preclinical models.
Bacteriophages transferred during FMT may drive horizontal gene transfer, altering microbial function and antibiotic resistance in ways science has largely ignored.
A microbial enzyme from Bifidobacterium enhances anti-TNF therapy efficacy in IBD by reshaping immune regulation via histone lactylation.
New review reveals how gut microbe chemicals directly reprogram tumor immune responses through multiple pathways.
Regular physical activity slashes chronic pancreatitis risk and attenuates disease progression via muscle-derived vesicles that quiet pancreatic inflammation.