Sunitinib Shows Promise After Immunotherapy Failure in Kidney Cancer
A phase II trial tests whether sunitinib retains activity in metastatic renal cell carcinoma after first-line immunotherapy resistance.
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A phase II trial tests whether sunitinib retains activity in metastatic renal cell carcinoma after first-line immunotherapy resistance.
A Phase 1 trial examines if the triple-agonist GLP-1 drug retatrutide changes how the body processes the beta-blocker metoprolol.
A completed RCT tests whether 6 months of moderate aerobic exercise protects memory and brain structure in older adults at genetic risk for Alzheimer's.
A Phase 3 trial evaluates a next-generation quadrivalent influenza vaccine against existing options, testing both immune response and manufacturing consistency.
A completed trial finds Mat Pilates training may reduce arterial stiffness and improve vascular function in obese premenopausal women.
A first-in-human Phase 1 trial evaluates PF-07257876, a dual-checkpoint bispecific antibody targeting both CD47 and PD-L1, in hard-to-treat cancers.
A Phase II NCI trial testing bintrafusp alfa in metastatic urothelial carcinoma was terminated after enrolling only 2 patients.
A 2-year clinical trial testing Juice Plus+ products against low-grade inflammation and biological aging markers in overweight seniors was terminated before completion.
A Phase 2 trial testing rituximab, infliximab, and tocilizumab for hard-to-treat non-ANCA vasculitis was terminated before completion.
A completed RCT tests whether adding collagen peptides to standard calcium and vitamin D supplementation improves bone density and remodeling markers in women with osteopenia.
A Phase 1/2 trial explores combining KIR, PD-1, and CTLA-4 inhibitors to unlock stronger anti-tumor immunity.
A completed trial compares two endometrial prep strategies for IVF patients with moderate-to-severe intrauterine adhesions, a notoriously difficult fertility challenge.