10,107 articles
A gut bacterium elevated in Parkinson's patients produces a metabolite that crosses into the brain, triggering dopaminergic neuron loss and motor deficits.
A gut-derived compound, indole-3-propionate, slashes amyloid plaques, tames neuroinflammation, and rescues cognition in AD mouse models.
A prospective MRI study of 281 patients maps how cerebral blood flow fluctuates during reversible cerebral vasoconstriction syndrome, linking perfusion to vascular findings.
A newly mapped molecular axis—ZNF384 → Fibulin-1 → TGF-β/Smad3—accelerates artery stiffening by triggering smooth muscle cell senescence and fibrosis.
TERT-deficient progeria mice reveal how aging-related mitochondrial dysfunction triggers cardiac electrical and structural remodelling.
A new study links elevated PAI-1 to accelerated arterial stiffness and shows that reducing or inhibiting PAI-1 protects the vasculature and extends lifespan.
A machine learning model using sleep, loneliness, and life satisfaction predicts depression in cardiovascular metabolic disease patients with 82% accuracy.
A simple insulin resistance metric predicts accelerated biological aging and higher mortality in cardiovascular-kidney-metabolic syndrome patients.
A large UK Biobank study links 77 plasma metabolites to brain age gap, with HDL lipid fractions showing the strongest signals.
A landmark 2023 Nutrition Society conference tackled how diet, lifestyle, and precision nutrition can prevent and manage multiple chronic diseases.
A 2025 systematic review of 32 studies finds VNS improves motor and non-motor symptoms in Parkinson's, tremor, dystonia, and Tourette's syndrome.
New review reveals how stimulating the vagus nerve calms runaway immune responses, offering hope for RA, Crohn's, and lupus patients.
