Stem Cells

415 articles in this topic

First PROTAC Reaches FDA Filing After Phase 3 Win — A New Era in Drug Design
Regenerative Medicine

First PROTAC Reaches FDA Filing After Phase 3 Win — A New Era in Drug Design

Arvinas' vepdegestrant becomes the first PROTAC to clear Phase 3 trials, targeting disease proteins for destruction rather than just blocking them.

Press Release
Jul 4, 2026 0
Engineered Mammary Organoids Act as Living Drug Depots to Fight Breast Cancer Recurrence
Regenerative Medicine

Engineered Mammary Organoids Act as Living Drug Depots to Fight Breast Cancer Recurrence

Scientists engineer mammary organoids that secrete anticancer drugs while simultaneously regenerating functional breast tissue after surgery.

Research Paper
Jul 4, 2026 0
Japan Sets New Rules for Stem Cell Embryo Model Research in 2026
Regenerative Medicine

Japan Sets New Rules for Stem Cell Embryo Model Research in 2026

Japan's April 2026 revised guidelines now govern stem cell-based embryo models, marking a global regulatory milestone.

Research Paper
Jul 4, 2026 0
Smart Microneedle Stent Seals Intestinal Surgery Sites and Delivers Drugs On Demand
Regenerative Medicine

Smart Microneedle Stent Seals Intestinal Surgery Sites and Delivers Drugs On Demand

A biodegradable microneedle stent achieves sutureless intestinal anastomosis while releasing anti-inflammatory drugs triggered by local inflammation.

Research Paper
Jul 4, 2026 0
CAR T Cell Therapy Targets Mutant Calreticulin to Selectively Destroy Myelofibrosis Cells
Regenerative Medicine

CAR T Cell Therapy Targets Mutant Calreticulin to Selectively Destroy Myelofibrosis Cells

A precision CAR T cell therapy wipes out disease-driving myelofibrosis stem cells while sparing healthy ones — a potential cure candidate.

Research Paper
Jul 4, 2026 0
Massive CRISPRi Atlas Maps How 11,692 Genes Control Human Stem Cells
Regenerative Medicine

Massive CRISPRi Atlas Maps How 11,692 Genes Control Human Stem Cells

Researchers silenced nearly every expressed gene in human iPSCs, creating a landmark map of pluripotency's genetic architecture.

Research Paper
Jul 4, 2026 0
Prime Editing Unlocks Hidden Drug-Making Power of Filamentous Fungi
Regenerative Medicine

Prime Editing Unlocks Hidden Drug-Making Power of Filamentous Fungi

A new prime editing approach gives scientists precise genetic control over filamentous fungi, opening the door to novel bioactive compounds.

Research Paper
Jul 4, 2026 0
RNA Base Editing Upgraded With Smarter Guide RNAs Mimicking Natural ADAR Targets
Regenerative Medicine

RNA Base Editing Upgraded With Smarter Guide RNAs Mimicking Natural ADAR Targets

Researchers improve ADAR-based RNA editing precision using guide RNAs modeled on highly edited natural substrates.

Research Paper
Jul 4, 2026 0
Coral Symbiosis Secret Revealed: Lysosomes Power Algae-Hosting Organelles
Regenerative Medicine

Coral Symbiosis Secret Revealed: Lysosomes Power Algae-Hosting Organelles

Scientists uncover how corals repeatedly evolved a specialized organelle to house algal partners — by hijacking their own lysosomal machinery.

Research Paper
Jul 4, 2026 0
Mechanosensitive Ion Channel Found to Drive Liver Regeneration After Injury
Regenerative Medicine

Mechanosensitive Ion Channel Found to Drive Liver Regeneration After Injury

A newly identified pressure-sensing channel in liver cells may hold the key to unlocking faster, more complete liver repair.

Review
Jul 4, 2026 0
Chronic Stress Ages Your Blood Stem Cells Via a Brain-Gut-Bone Marrow Pathway
Regenerative Medicine

Chronic Stress Ages Your Blood Stem Cells Via a Brain-Gut-Bone Marrow Pathway

Psychological stress impairs hematopoietic stem cells by suppressing brain regions, depleting gut microbiome-derived spermidine, and triggering ferroptosis.

Research Paper
Jul 3, 2026 0
Inherited Bone Marrow Failure Syndromes Explained from Root Causes to Clinical Signs
Regenerative Medicine

Inherited Bone Marrow Failure Syndromes Explained from Root Causes to Clinical Signs

A comprehensive review of inherited bone marrow failure, covering genetic causes, major syndromes, and the cytopenias that define them.

Research Paper
Jul 2, 2026 0
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