Brain Health
Spinal Cord Tau Tangles Drive Alzheimer's Touch Loss and Cognitive Decline
New research links spinal cord tau pathology to tactile deficits and cognitive impairment in Alzheimer's via disrupted CCK neurons.
Research Paper
Jul 4, 2026 0
Topic
Alzheimer's
Alzheimer's disease research, amyloid plaques, tau tangles, and cognitive decline
407 articles
Brain Health
Small Molecule XL20 Extends ALS Mouse Survival by Targeting TDP-43 Toxicity
A brain-penetrant compound targets a key region of TDP-43, reducing motor neuron loss and extending survival in ALS mouse models.
Research Paper
Jul 4, 2026 0
Brain Health
Women's Midlife Is the Critical Window for Alzheimer Prevention
Two-thirds of Alzheimer cases are women. New evidence shows menopause transition—not just aging—drives that risk, opening a prevention window.
Research Paper
Jul 3, 2026 0
Brain Health
Having Multiple Chronic Diseases Accelerates Brain Aging in Older Adults
New research links multimorbidity — especially cardiometabolic disease clusters — to measurable brain-age acceleration in dementia-free older adults.
Research Paper
Jul 3, 2026 0
Brain Health
Lipid Droplets Trigger Alpha-Synuclein Clumping That Kills Dopamine Neurons
New research reveals how lipid droplets spark the protein aggregation at the heart of Parkinson's disease, disrupting energy metabolism.
Research Paper
Jul 3, 2026 0
Brain Health
Your VO2 Max in Your 70s Could Cut Alzheimer's Risk in Half
Older adults with higher cardiorespiratory fitness had ~48% lower Alzheimer's risk over 8.7 years, with a clear VO2 threshold identified.
Research Paper
Jul 3, 2026 0
Brain Health
BCG Vaccine Reprograms Brain Immunity and Shifts Alzheimer's Biomarkers
Two small clinical trials show BCG vaccination alters immune activity in cerebrospinal fluid and changes amyloid-β levels in older adults.
Research Paper
Jul 3, 2026 0
Brain Health
Home-Based Exercise and Brain Training Tackles Cognitive Decline in Older Adults
A Canadian RCT tests whether virtual aerobic, resistance, and cognitive training can feasibly combat mild cognitive impairment at home.
Clinical Trial
Jul 3, 2026 0
Brain Health
Home Aerobic Exercise Beats Balance Training for Cerebellar Ataxia in 12-Month RCT
High-intensity home cycling improved ataxia symptoms, fatigue, and VO2max significantly more than dose-matched balance training over one year.
Research Paper
Jul 2, 2026 0
Brain Health
Schizophrenia and Dementia Share Genetic Roots at Brain Vulnerability Hotspot
A large-scale genomic study identifies 39 shared genetic loci between schizophrenia and Alzheimer's disease, converging on chromosome 16p11.2.
Research Paper
Jul 2, 2026 0
Brain Health
High Resistin Levels Linked to Greater Alzheimer's Risk in Older Adults
A nested study within the PREDIMED trial finds elevated resistin — an adipose-derived hormone — associated with 56% higher odds of incident Alzheimer's disease.
Research Paper
Jul 2, 2026 0
Brain Health
Blood Protein Signatures Reveal Alzheimer's Pathology in African Populations
First large proteomic study in Nigerian and Tanzanian adults links plasma proteins to amyloid pathology, expanding Alzheimer's biomarker research beyond Western cohorts.
Research Paper
Jul 2, 2026 0
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