Delirium May Be the Hidden Bridge Between Severe Infection and Dementia
New research proposes delirium as the key mechanistic link explaining why severe infections dramatically raise dementia risk.
Alzheimer's disease research, amyloid plaques, tau tangles, and cognitive decline
407 articles
New research proposes delirium as the key mechanistic link explaining why severe infections dramatically raise dementia risk.
New research reveals normal Tau protein limits mitochondrial efficiency — its absence boosts energy output and stress resistance.
New research identifies plasma and CSF tau biomarkers that closely mirror tau PET scans, potentially replacing costly brain imaging.
A large study of 2,795 adults finds OSA is associated with worse memory and elevated dementia risk scores, partly explained by vascular risk factors.
New review links physical activity to glymphatic function — the brain's built-in detox network that flushes neurotoxic proteins.
A Lancet systematic review finds interactive, personalized dementia prevention programs outperform mass media campaigns in changing real-world behavior.
A rigorous 176-sample study finds cerebrospinal fluid is truly sterile, refuting claims of a resident CSF microbiome even in Alzheimer's patients.
A scoping review of 11 studies finds consistent links between oral disease and AD severity, but no clear proof that treating oral health improves cognition.
A newly identified TFEB-ATP6V0C axis in microglia controls alpha-synuclein clearance — and restoring it reduces Parkinson's pathology in mice.
A landmark Nature Immunology review reveals adaptive immune cells actively shape neurodegeneration — and could be targeted therapeutically.
A landmark review reveals astrocytes as active immune players whose dysfunction drives Alzheimer's, Parkinson's, MS, and ALS.
A key FDA-approved Alzheimer's blood biomarker loses more than half its diagnostic accuracy in veterans with prior traumatic brain injury.