T Cells and B Cells Are Driving Alzheimer's and Parkinson's Disease
A landmark Nature Immunology review reveals adaptive immune cells actively shape neurodegeneration — and could be targeted therapeutically.
Alzheimer's disease research, amyloid plaques, tau tangles, and cognitive decline
410 articles
A landmark Nature Immunology review reveals adaptive immune cells actively shape neurodegeneration — and could be targeted therapeutically.
A landmark review reveals astrocytes as active immune players whose dysfunction drives Alzheimer's, Parkinson's, MS, and ALS.
A key FDA-approved Alzheimer's blood biomarker loses more than half its diagnostic accuracy in veterans with prior traumatic brain injury.
UCLA researchers found long-term chlorpyrifos exposure more than doubles Parkinson's risk and damages dopamine neurons directly.
A new metabolomics study links diet and exercise to blood pathway scores that track cognitive and physical decline across CN, MCI, and Alzheimer's stages.
A major meta-analysis of 222,108 people links higher vegetable and fruit intake to significantly lower dementia risk, with green leafy vegetables standing out.
A new biomarker study shows CSF TMEM106B protein drops with worsening FTD and predicts brain shrinkage and faster decline.
A paradigm-shifting review proposes that α-synuclein pathology originates in the kidneys and spreads to the brain via PKC signaling.
A new review links BPA exposure from common plastic products to key Alzheimer's mechanisms including amyloid buildup, tau pathology, and cognitive decline.
New research links mitochondrial dysfunction in microglia to cellular senescence, revealing a key driver of brain aging.
A prospective trial finds 15 days of gamma-frequency tACS improves memory, attention, and executive function in mild Alzheimer's disease.
An interpretable machine learning model using MRI brain texture features diagnosed and staged Parkinson's disease with up to 90% accuracy across multiple centers.