Topic

Alzheimer's

Alzheimer's disease research, amyloid plaques, tau tangles, and cognitive decline

410 articles

Cilostazol Tested Against Cognitive Decline in Mild Cognitive Impairment
Brain Health

Cilostazol Tested Against Cognitive Decline in Mild Cognitive Impairment

A Phase 2 trial explores whether cilostazol, a blood thinner with brain-protective effects, can slow memory loss in MCI patients.

Clinical Trial
Jun 27, 2026 0
Delirium May Be the Hidden Bridge From Severe Infection to Dementia
Brain Health

Delirium May Be the Hidden Bridge From Severe Infection to Dementia

New research proposes delirium as the key mechanistic link explaining why severe infections dramatically raise long-term dementia risk.

Research Paper
Jun 27, 2026 0
Stressed Microglia Turn Senescent and Trigger Brain Degeneration
Brain Health

Stressed Microglia Turn Senescent and Trigger Brain Degeneration

When mitochondria in brain immune cells misfire, they disrupt neuronal communication and accelerate the very aging they should prevent.

Research Paper
Jun 27, 2026 0
Blood Metabolite Ergothioneine Linked to Cognition and Alzheimer's Risk in Midlife
Brain Health

Blood Metabolite Ergothioneine Linked to Cognition and Alzheimer's Risk in Midlife

A study of 991 blood metabolites finds ergothioneine has the strongest association with cognition, and antacid use may deplete it.

Research Paper
Jun 25, 2026 0
New Blood Test for Alzheimer's Needs Less Sample and Beats PET Scan Accuracy
Brain Health

New Blood Test for Alzheimer's Needs Less Sample and Beats PET Scan Accuracy

A streamlined mass spectrometry assay detects preclinical Alzheimer's from just 100 µL of blood with AUC 0.81 vs 0.65 for previous methods.

Research Paper
Jun 24, 2026 0
Scientists Identify a Distinct Motor Neuron State That Predicts ALS Cell Death
Brain Health

Scientists Identify a Distinct Motor Neuron State That Predicts ALS Cell Death

Researchers mapped a conserved molecular signature in motor neurons that emerges before cell death in ALS, pointing to new therapeutic targets.

Research Paper
Jun 24, 2026 0
Museum Cultural Pathways Beat Sedentary Lifestyle in Adults Over 50
Brain Health

Museum Cultural Pathways Beat Sedentary Lifestyle in Adults Over 50

A completed trial tests whether gamified museum walks can replace traditional exercise for sedentary older adults.

Clinical Trial
Jun 23, 2026 0
Oral GLP-1 Drug Crosses Blood-Brain Barrier to Reverse Alzheimer's Metabolism
Brain Health

Oral GLP-1 Drug Crosses Blood-Brain Barrier to Reverse Alzheimer's Metabolism

A new oral GLP-1 receptor agonist penetrates the brain, restoring astrocyte-neuron metabolic crosstalk disrupted in Alzheimer's disease.

Research Paper
Jun 23, 2026 0
Tubulin Protein May Stop Alzheimer's and Parkinson's Toxic Clumps From Forming
Brain Health

Tubulin Protein May Stop Alzheimer's and Parkinson's Toxic Clumps From Forming

Baylor scientists find tubulin redirects rogue brain proteins away from toxic aggregates, pointing to a novel neurodegenerative disease strategy.

Press Release
Jun 22, 2026 0
Partial Reprogramming of Memory Cells Reverses Cognitive Aging in Mice
Brain Health

Partial Reprogramming of Memory Cells Reverses Cognitive Aging in Mice

OSK gene therapy targeting engram neurons restored memory to youthful levels in aged mice and Alzheimer's models, reversing senescence hallmarks.

Research Paper
Jun 22, 2026 0
DBT Skills Training Targets Suicide Risk in Alzheimer's Caregivers
Brain Health

DBT Skills Training Targets Suicide Risk in Alzheimer's Caregivers

A completed pilot trial tests adapted Dialectical Behavior Therapy to reduce suicidality in aging family caregivers of AD/ADRD patients.

Clinical Trial
Jun 21, 2026 0
Scientists Reprogram Brain Immune Cells to Clear Alzheimer's Plaques
Brain Health

Scientists Reprogram Brain Immune Cells to Clear Alzheimer's Plaques

A molecule called OLE restores microglia's protective function, reducing amyloid plaques and improving memory in animal models.

Press Release
Jun 20, 2026 0
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