Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1,773 articles
A comprehensive review of pNETs covers genetics, clinical syndromes, imaging, and evolving therapies with 90% survival in low-grade cases.
A five-compound oral drug targeting mTOR, autophagy, NAD+, and senescence extended median lifespan 33% and cut frailty progression 70% in aged mice.
Go beyond the basics and explore how sestrins work at the molecular level — regulating AMPK, mTORC1, and autophagy to coordinate your cell's response to stress and aging.
A short Nature Aging item flags that some age-related molecular changes appear to occur independently of exercise. Only the title is available; details await full-text review.
A new review unpacks the molecular and physiological secrets behind the world's longest-lived vertebrate.
Key enzymes like AMPK and mTOR orchestrate communication between cellular organelles — and their failure may drive aging and neurodegeneration.
A major review reveals how cellular senescence and biological aging clocks intersect to reshape cancer immunity and treatment strategy.
A landmark review traces how epigenetic editing — rewriting gene expression without touching DNA — is entering its first clinical trials.
VNS is FDA-approved for epilepsy and depression, and emerging research targets autoimmune and chronic inflammatory conditions.
Meet sestrins — the remarkable proteins your cells make when under stress that may hold the key to healthier, longer aging. No science degree required.
New research reveals how defective newly-made proteins expose hidden molecular tags, triggering rapid cellular cleanup.
A new review reveals how natural compounds could modulate EZH2 — a critical epigenetic enzyme — to slow aging without the risks of strong drug inhibition.
