Stem cell therapies, regenerative medicine, tissue engineering, and cellular reprogramming
203 articles
Scientists engineer mammary organoids that secrete anticancer drugs while simultaneously regenerating functional breast tissue after surgery.
Japan's April 2026 revised guidelines now govern stem cell-based embryo models, marking a global regulatory milestone.
A precision CAR T cell therapy wipes out disease-driving myelofibrosis stem cells while sparing healthy ones — a potential cure candidate.
Researchers silenced nearly every expressed gene in human iPSCs, creating a landmark map of pluripotency's genetic architecture.
Psychological stress impairs hematopoietic stem cells by suppressing brain regions, depleting gut microbiome-derived spermidine, and triggering ferroptosis.
Adding a vascular network to stem cell-derived islet organoids dramatically improves beta-cell calcium signaling, insulin secretion, and diabetes reversal in mice.
A short-term drug combo rejuvenates aged mesenchymal stem cells, boosting proliferation and reducing inflammatory markers in vitro.
A new review maps how blood stem cell metabolism shifts with aging and how leukemia hijacks those changes — pointing to targeted therapeutic strategies.
A new review traces how aging science evolved from single-cause theories to partial reprogramming with Yamanaka factors as a lifespan-extending strategy.
Master the cutting-edge molecular pharmacology of Wnt pathway modulation — from small-molecule β-catenin activators to senescence-driven inhibitor networks — and understand how researchers are translating these mechanisms into regenerative therapies.
Senescent endothelial cells that accumulate after bone injury sabotage stem cell repair — and quercetin delivered locally can reverse this.
Go beyond the basics to understand how Wnt ligands, receptor complexes, and beta-catenin destruction machinery orchestrate stem cell behavior — and why these mechanisms break down with age.
