Alzheimer's disease research, amyloid plaques, tau tangles, and cognitive decline
177 articles
New spatial brain mapping identifies specific cortical layers most at risk and reveals how genetics influence dementia progression.
New research reveals how early life adversity fundamentally alters how our brains age, affecting memory and decision-making abilities.
Researchers discover a phospholipid derivative that protects brain cells by calming overactive immune cells in dementia-prone mice.
New brain imaging technology detects subtle changes in older adults who worry about their memory, potentially identifying decline years earlier.
New research reveals how specific brain wave patterns mediate memory decline with age, offering potential intervention targets.
New research identifies specific blood markers that independently predict both physical frailty and cognitive decline.
New research reveals mitochondrial dysfunction as the starting point of Alzheimer's disease, offering early intervention targets.
ABCA7 gene variant shows stronger brain connectivity changes than APOE-ε4 in older African Americans at risk for dementia.
Probucol, a discontinued cholesterol medication, may boost brain-protective proteins in older adults at risk for dementia.
Three existing drugs, including a shingles vaccine, emerge as top candidates for repurposing against Alzheimer's disease.
Study tested whether pimavanserin could prevent return of hallucinations and delusions in dementia patients who initially responded to treatment.
USC researchers discover people with Down syndrome and Alzheimer's have twice the brain iron levels, triggering damaging cell death.
