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Injectable Nanozyme-miRNA System Reverses Cartilage Aging in Osteoarthritis
Regenerative Medicine

Injectable Nanozyme-miRNA System Reverses Cartilage Aging in Osteoarthritis

A novel injectable platform combining miR-197-3p and Prussian blue nanozymes reverses chondrocyte senescence and restores cartilage in OA models.

Articolo scientifico
5 lug 2026 0
How TDP-43 Malfunction Turbocharges Alzheimer's Tau Pathology
Brain Health

How TDP-43 Malfunction Turbocharges Alzheimer's Tau Pathology

Johns Hopkins researchers reveal how TDP-43 loss accelerates toxic tau buildup, uncovering a key mechanism in Alzheimer's and related dementias.

Articolo scientifico
5 lug 2026 0
GLP-1 Drugs Cut Heart Failure Risk Within 6 Months in Obese Patients
Heart Health

GLP-1 Drugs Cut Heart Failure Risk Within 6 Months in Obese Patients

A meta-analysis of 4 RCTs finds semaglutide and tirzepatide significantly reduce worsening heart failure events in obese patients within 5–6 months.

Articolo scientifico
5 lug 2026 0
Mass Cytometry Uncovers Hidden Immune Changes Before Type 1 Diabetes Strikes
Metabolic Health

Mass Cytometry Uncovers Hidden Immune Changes Before Type 1 Diabetes Strikes

Imaging 16 million pancreatic cells reveals macrophage-T cell interactions and beta-cell stress signatures at the earliest, preclinical stages of type 1 diabetes.

Articolo scientifico
5 lug 2026 0
Pyruvate Directly Rewrites Your Epigenome When Blood Sugar Spikes
Metabolic Health

Pyruvate Directly Rewrites Your Epigenome When Blood Sugar Spikes

A new PTM called lysine pyruvylation links glycolytic activity directly to gene regulation, with SIRT3 acting as the eraser.

Articolo scientifico
5 lug 2026 0
Brain Shrinkage and White Matter Damage Together Predict Cognitive Decline
Brain Health

Brain Shrinkage and White Matter Damage Together Predict Cognitive Decline

A new index combining brain atrophy, white matter lesions, and cognition reveals who maintains brain health with age — and who doesn't.

Articolo scientifico
5 lug 2026 0
Ginsenoside Rg1 Doubles Muscle Stem Cells in Older Women After Resistance Training
Exercise & Fitness

Ginsenoside Rg1 Doubles Muscle Stem Cells in Older Women After Resistance Training

A small but rigorous crossover trial shows a ginseng compound dramatically boosts muscle stem cells and mitochondrial content in women over 60.

Articolo scientifico
5 lug 2026 0
Probiotics May Slow Cognitive Decline by Restoring the Aging Gut-Brain Axis
Gut & Microbiome

Probiotics May Slow Cognitive Decline by Restoring the Aging Gut-Brain Axis

Gut dysbiosis drives brain aging — and targeted probiotics may help reverse it. Here's what the latest review reveals.

Revisione
5 lug 2026 0
Natural Compounds May Fine-Tune a Key Aging Enzyme Better Than Drugs
Longevity & Aging

Natural Compounds May Fine-Tune a Key Aging Enzyme Better Than Drugs

A new review reveals how natural compounds could modulate EZH2 — a critical epigenetic enzyme — to slow aging without the risks of strong drug inhibition.

Revisione
5 lug 2026 0
Dominic D'Agostino on Ketogenic Therapy, Ketone Supplements, and Hyperbaric Oxygen for Brain Injury
Metabolic Health

Dominic D'Agostino on Ketogenic Therapy, Ketone Supplements, and Hyperbaric Oxygen for Brain Injury

Dom D'Agostino returns to STEM-Talk to unpack 20+ new papers on ketogenic metabolic therapy for cancer, ketone supplement safety, and HBOT for TBI.

Podcast
5 lug 2026 0
Ido Portal on How Playful Movement Rewires Your Brain and Nervous System
Brain Health

Ido Portal on How Playful Movement Rewires Your Brain and Nervous System

Movement coach Ido Portal reveals how play, transitions states, and bodily awareness can reshape stress responses and deepen mind-body connection.

Podcast
5 lug 2026 0
Blood Rejuvenation and Epigenetic Reset May Work Better Together Against Aging
Longevity & Aging

Blood Rejuvenation and Epigenetic Reset May Work Better Together Against Aging

A new review argues that systemic blood recalibration and partial cellular reprogramming target different axes of aging and should be combined.

Revisione
5 lug 2026 0
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