Spermine Acts as Molecular Glue to Clear Alzheimer's and Parkinson's Proteins
New research reveals how spermine promotes protein condensation and autophagy to combat neurodegeneration in lab models.
20 artigos
New research reveals how spermine promotes protein condensation and autophagy to combat neurodegeneration in lab models.
A new partnership brings standardized spermidine into US clinical settings, shifting longevity science from shelves to physician-guided care.
Vá além do básico e explore os mecanismos moleculares precisos pelos quais as poliaminas retardam o envelhecimento celular — da indução da autofagia à regulação epigenética e à proteção cardiovascular.
Oxford researchers tested whether spermidine could rejuvenate aging immune systems and improve vaccination effectiveness in adults over 65.
A double-blind RCT finds daily spermidine supplementation reverses immune senescence markers and boosts vaccine antibody responses in adults over 65.
Novel KH-1 supplement containing spermidine and probiotics tested for autophagy stimulation and glucose control in 42 prediabetic participants.
New research reveals spermidine supplements and low-protein diets independently protect against brain aging in fruit flies.
New research reveals how polyamine molecules regulate cellular aging and may offer promising anti-aging interventions.
New research reveals how these two popular longevity supplements target different cellular pathways for anti-aging benefits.
Domine a visão sistêmica completa da biologia das poliaminas — do controle do fluxo biossintético e das modificações pós-traducionais ao design de ensaios clínicos e às estratégias terapêuticas emergentes.
Descubra o fascinante mundo das poliaminas — compostos naturais encontrados nos alimentos e produzidos pelo próprio organismo que os pesquisadores estão associando a vidas mais longas e saudáveis.
NAD+ precursor supplementation restored fertility markers and improved embryo development in diabetes-induced reproductive dysfunction.
Pyrroloquinoline quinone at 5 μM improved porcine oocyte maturation, reduced ROS, and raised blastocyst formation rates in a new lab study.
New research shows pyrroloquinoline quinone improves egg maturation and embryo development in animal models.
New research reveals how polyamines flip from supporting healthy aging to turbocharging tumor growth through different cellular pathways.
Study shows nicotinamide mononucleotide (NMN) restores NAD+ levels and reverses declining oocyte quality in polycystic ovary syndrome.
Nanoplásticos de poliestireno de 50 nm acumulam-se nos testículos de camundongos, degradando a qualidade dos espermatozoides e desencadeando morte celular dependente de ferro por meio de uma via mitocondrial recém-identificada.
Natural compound improves egg quality and pregnancy outcomes in aging mice, offering hope for age-related infertility treatment.
Dasatinib and quercetin nanoparticles improve egg quality and fertility in aging mouse ovaries by clearing senescent cells.
Systematic review finds NMN enhances mitochondrial function and reduces oxidative stress in oocytes across multiple animal models.