New Autophagy Activator AA-20 Extends Worm Lifespan Without Blocking mTOR
Small molecule AA-20 clears protein aggregates and lipid droplets, extending C. elegans lifespan through a novel mTOR-independent autophagy pathway.
20 articles
Small molecule AA-20 clears protein aggregates and lipid droplets, extending C. elegans lifespan through a novel mTOR-independent autophagy pathway.
Expert reviews compare NMN and NR head-to-head. NMN edges out for muscle and sleep benefits; NR leads for neuroprotection.
Expert reviews compare NMN and NR on human trial data, bioavailability, and top-ranked brands for 2026.
A comparative review of NMN and NR supplements weighs tissue targeting, clinical evidence, and top-rated products for NAD+ optimization.
A landmark review reveals obesity and aging share molecular hallmarks that accelerate cardiovascular disease, and how anti-obesity drugs may reverse this.
A comprehensive review reveals how age-remodeled microenvironments cripple satellite cells, driving muscle lossβand how emerging therapies may reverse it.
A new partnership brings standardized spermidine into US clinical settings, shifting longevity science from shelves to physician-guided care.
Go beyond the basics to understand how your cells detect nutrient scarcity and orchestrate autophagy through mTORC1, AMPK, and lysosomal signaling β the molecular logic behind cellular self-renewal.
Go beyond the basics and explore the molecular machinery behind autophagy β from the three distinct recycling pathways to the key sensors that tell your cells when to clean house.
Expert reviews rank fisetin and quercetin as top senolytics, with spermidine and resveratrol as supporting players in longevity supplement stacks.
A product review breaks down the evidence tiers for four popular longevity supplements and rates the best commercial stacks.
A leading aging researcher audits NMN, urolithin A, spermidine, and more β revealing what actually works and what falls short.
Expert reviews compare leading senolytic and NAD+ supplement brands on ingredients, evidence quality, and value.
New expert reviews compare NMN and NR head-to-head, ranking top products by purity, absorption, and clinical evidence.
Comprehensive review reveals how cellular recycling process autophagy mediates benefits of diet, exercise, and longevity drugs across species.
New research reveals spermidine supplements and low-protein diets independently protect against brain aging in fruit flies.
New research reveals how cancer radiation treatment causes muscle weakness through a previously unknown tumor-muscle communication pathway.
New research reveals how hepatoma cells evade immunotherapy by secreting N1-acetylspermidine to suppress immune function.
Leading neuroscientist reveals how strategic stress through fasting and exercise triggers powerful anti-aging adaptations in the brain and body.
New research reveals how these two popular longevity supplements target different cellular pathways for anti-aging benefits.