Cognitive performance, neuroplasticity, dementia prevention, and brain aging research
889 artigos
A bibliometric analysis of 595 papers maps how glymphatic-Alzheimer's research has grown exponentially, pinpointing AQP4, sleep, and DTI-ALPS imaging as the hottest frontiers.
Cerebral hypoperfusion drives glymphatic dysfunction in systemic inflammation — and restoring blood flow with levosimendan reverses it.
HIE disrupts the glymphatic system in neonatal brains, impairing waste clearance and development with lasting consequences.
A comprehensive review details how NMOSD, MOGAD, and other rare CNS disorders are frequently mistaken for MS — and how to tell them apart.
A completed RCT tests whether treating insomnia with CBT-I can improve cognition and slow amyloid buildup in adults aged 60–85.
Boosting BNIP3 in muscle tissue extends fly lifespan and shields the brain from age-related degeneration via a muscle-brain signaling axis.
A multi-omics analysis of over 1 million brain cells reveals how neurotransmitter systems change across aging and eight neuropsychiatric disorders.
A major review reveals how the glymphatic system's failure drives neurodegeneration and brain tumor resistance — and how to fix it.
Blocking brain lymphatic drainage triggers age-dependent compensatory responses — young rats adapt, middle-aged rats largely cannot, with proteomic signs of neurodegeneration in both.
New mouse study reveals how the brain's waste-clearance system modulates toxic protein buildup linked to Parkinson's disease.
PET-MRI study of 54 cSVD patients links microglial activation to enlarged white matter perivascular spaces, not BBB leakage.
Inhibiting TRPV4 channels in mice restored glymphatic drainage, cut cerebral edema, and improved neurological recovery after ischemic stroke.
