Cognitive performance, neuroplasticity, dementia prevention, and brain aging research
889 artigos
A phase 2/3 trial of the BACE inhibitor atabecestat in amyloid-positive asymptomatic adults was terminated before completion, raising questions about this drug class.
A completed Canadian platform trial enrolls 354 at-risk adults in a multidomain online brain health program targeting dementia prevention.
A Cochrane meta-analysis of 8 RCTs finds most pharmacological treatments fail to improve ataxia scores, though upper limb dexterity may benefit.
A new study warns that diabetes medications could confound Alzheimer's biomarker studies, distorting our understanding of the diabetes-dementia link.
A formal erratum updates a 2026 cross-sectional survey on mental health factors affecting early-career dementia researchers worldwide.
A key potassium channel, KCNA4, is lost in vulnerable brainstem neurons at Braak II — potentially fueling tau pathology progression.
A real-time brain-computer interface decodes auditory attention and amplifies the speaker you choose, beating today's hearing aids.
New research pinpoints the hippocampal dorsal CA1 as the neural hub encoding individual differences in prosocial vs. selfish behavior.
IRISeq maps gene expression across aging mouse brains, finding lymphocytes fuel neuroinflammation and accelerate cellular aging.
A New England Journal of Medicine perspective argues that healthcare AI risks deepening inequities for underserved populations.
A NEJM perspective piece explores the hidden meaning and emotional depth found in everyday clinical encounters.
A cerebral syphilitic gumma case published in NEJM reminds clinicians that neurosyphilis can mimic brain tumors and must stay on the differential.
