Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1.644 artigos
α-Lipoic acid declines in aged human intestines and supplementation reverses stem cell aging via Paneth cell mTOR inhibition.
A cryo-EM structural study reveals mTORC2 recognizes Akt's 3D protein fold—not just its local sequence—to achieve remarkable substrate selectivity.
A landmark review reveals how lysosomal membrane damage triggers repair, death, or renewal — with major implications for aging and disease.
Descubra como um minúsculo interruptor molecular dentro das suas células controla o crescimento, o uso de energia e a velocidade do seu envelhecimento — e o que você pode fazer para mantê-lo em equilíbrio.
UCSF researchers find older adults with 'normal' B12 still show cognitive slowing and brain white matter damage.
Scientists find phosphatidylcholine loss fragments mitochondrial networks with age — and supplementing it may help reverse the damage.
New CRISPR platform quiets PCSK9 cholesterol gene for 18 months in primates — no permanent DNA edits required.
New York biotech reports a favorable safety profile for OLX-07010, an oral drug designed to stop toxic tau protein clumping in the brain.
China's first standardized longevity medicine curriculum trains doctors in aging biology, cardiometabolic prevention, and AI-assisted care.
Researchers show that enhancing thymic epithelial cell activity in aged mice rebuilds naïve T-cell populations and dramatically improves survival after infection.
A comprehensive review deconstructs the thymic microenvironment using single-cell technologies, from embryonic formation through age-related involution.
A first-of-its-kind trial shows therapeutic plasma exchange plus IVIG reduced biological age by an average of 2.6 years, confirmed by multi-omics analysis.
