Stem cells, exosomes, gene therapy, peptides, hyperbaric oxygen, and epigenetic reprogramming
390 articoli
Cytosine base editing achieved 62–89% efficiency fixing a hyperinflammatory disease gene, but revealed distinct genotoxicity risks across cell types.
BIIB080 failed its primary endpoint in Phase 2, yet Biogen sees potential signals worth pursuing in the fight against Alzheimer's tau tangles.
Harvard-developed ENTER nanoparticles outperform lipid transfection reagents in delivering mRNA, CRISPR, proteins, and siRNA to diverse cell types.
A special issue overview surveys three decades of peptide-based materials research, spotlighting applications from drug delivery to regenerative medicine.
Tumor-infiltrating lymphocyte therapies are emerging as a powerful cancer treatment. Here's what the science says and why it matters for longevity.
A landmark clinical trial transplanted iPSC-derived dopamine neurons into Parkinson's patients using only tacrolimus — with no significant immune rejection.
Researchers 3D-printed silicone scaffolds seeded with human iPSC-derived spinal neural progenitor cells, transplanted them into transected rat spinal cords, and observed significant functional recovery at 12 weeks.
Adding methylene blue to ropivacaine in a serratus anterior plane block significantly prolongs pain relief up to 72 hours post-op.
Researchers erased imprinting marks in mouse sperm using dCas9-TET1, then traced how methylation partially recovered — fingering H3K9me3 as the key mediator.
Padroneggia la scienza all'avanguardia dell'ingegneria degli esosomi, della farmacocinetica di rilascio e della traduzione clinica — dalle nanoparticelle caricate con CRISPR alla logica molecolare delle terapie rigenerative di nuova generazione.
Eli Lilly suggests lower doses of tirzepatide may safely sustain weight loss at potentially lower cost, opening new options for long-term obesity management.
A Phase 1/2 trial tests four rounds of intrathecal MSC injections in ALS patients, targeting both safety and disease progression.
