Stem cells, exosomes, gene therapy, peptides, hyperbaric oxygen, and epigenetic reprogramming
390 articoli
Scientists converted fibroblasts into functional osteoblasts using small molecules, then formed transplantable spheroids that repair bone defects without scaffolding.
Radiation triggers a Ca²⁺-NFATc1-Fis1 cascade that fragments mitochondria in bone marrow stem cells, halting bone repair — and silencing Fis1 reverses it.
New wearable and non-invasive glucose monitors are transforming diabetes care — here's what's available and how they work.
Researchers used prime editing to introduce and then correct a de novo GDF11 nonsense mutation, revealing Golgi stress and broad transcriptomic dysregulation.
Amgen expands late-stage testing of its long-acting obesity drug MariTide, including a trial for patients switching from rival GLP-1 medications.
A comprehensive 2025 review maps the mechanisms, sources, and clinical applications of mesenchymal stem cells and their derived exosomes across cardiovascular, neurological, autoimmune, and musculoskeletal diseases.
Approfondisci la riprogrammazione parziale, il rimodellamento della nicchia, i senolitici e le terapie cliniche all'avanguardia — il toolkit molecolare per invertire l'invecchiamento delle cellule staminali.
Scopri cosa sono le cellule staminali, i diversi tipi presenti nel tuo corpo e perché sono essenziali per mantenere i tuoi organi in salute con l'avanzare dell'età.
Padroneggia i bersagli molecolari più avanzati, i dati degli studi clinici e le strategie terapeutiche emergenti volte a invertire l'invecchiamento della ECM — dalle combinazioni senolatiche agli scaffold bioingegnerizzati, fino alla riprogrammazione epigenetica.
A redesigned CRISPR system targets the chromosomal root cause of Down syndrome, opening new doors for genetic disease intervention.
Epicrispr's GEMS platform silences disease genes epigenetically — reversibly and safely — with a single viral vector, targeting FSHD and beyond.
Researchers at MIT outline strategies to precisely control the type and strength of immune responses triggered by mRNA vaccines.
