Alzheimer's disease research, amyloid plaques, tau tangles, and cognitive decline
368 articoli
Penn State researchers found abdominal contractions create pressure waves that gently rock the brain, boosting cerebrospinal fluid flow and waste clearance.
Raising Sox9 levels in aging astrocytes reduced amyloid plaque buildup and protected memory in mouse models with existing Alzheimer's symptoms.
A meta-analysis of 684,493 patients finds just 49% persist with anti-dementia drugs at 12 months, with major variation by drug type and study methodology.
A multi-cohort study finds that every 5 km closer to a lead-releasing facility is tied to measurably lower episodic memory scores.
Esplora i meccanismi molecolari alla base della salute cerebrale nel corso della vita — dalle cascate di segnalazione BDNF-TrkB e la neurogenesi ippocampale adulta alla clearance glinfatica dell'amiloide, fino agli interventi all'avanguardia che includono senolitici, agonisti GLP-1 e stimolazione transcranica.
Esplora ciò che accade realmente nel tuo cervello con l'avanzare dell'età — dal restringimento delle reti neuronali ai cambiamenti nei neurotrasmettitori — e scopri perché alcune persone mantengono una mente acuta ben oltre gli 80 anni.
Blocking the protein PTP1B boosted memory and cleared brain plaque in mice, with potential links to diabetes and obesity treatment.
A 2018 paper on antileukotriene therapy and tau phosphorylation in Alzheimer's mice has been retracted due to image fraud.
MethylCog, a 29-CpG blood test, indexes general cognitive ability and improves mild cognitive impairment detection beyond age and sex alone.
A 9-day intranasal insulin regimen restored working memory, recognition memory, and reduced neuroinflammation in mice engineered to mimic hippocampal aging.
Leading neurologists argue that amyloid aggregation dynamics may be distorting how we read clinical trial results for Alzheimer's immunotherapies.
A multi-omics subspace-merging algorithm identifies biologically distinct AD subtypes, pointing toward personalized treatment strategies.
