Cell Death Protein MLKL Triggers Inflammation Through Mitochondrial DNA Release
New research reveals how necroptosis activates immune pathways, offering targets for inflammatory bowel disease treatment.
Autoimmune diseases, immune modulation, inflammation, and self-tolerance
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New research reveals how necroptosis activates immune pathways, offering targets for inflammatory bowel disease treatment.
Comprehensive review explores how combining genomics, proteomics, and metabolomics advances psoriasis understanding and treatment.
New review reveals how immune cells orchestrate tissue scarring across organs, offering therapeutic targets for fibrosis affecting nearly a billion people.
New research reveals how lactate triggers lactylation, an epigenetic modification that fuels rheumatoid arthritis and lupus progression.
Natural flavonoid fisetin activates mitophagy and xenophagy pathways to restrict intracellular Salmonella growth in immune cells.
Study reveals how gut microbes transform T cells into potent autoimmune drivers that migrate to joints and promote arthritis.
New research reveals how a mitochondrial enzyme enhances immune cell function to fight bacterial lung infections and reduce inflammation.
New research reveals how immune cells use cysteine for both antioxidant defense and energy production, with major implications for cancer treatment.
Engineered immune cells offer new hope for treating kidney diseases that resist standard therapies, potentially improving long-term health outcomes.
Combining targeted therapies may help patients with severe hidradenitis suppurativa who don't respond to standard treatments.
New targeted therapies and biomarker-driven approaches are revolutionizing RA management, potentially improving healthspan for millions.
New research reveals how rheumatoid arthritis dramatically increases kidney disease risk through inflammation and medication effects.