Type 1 and type 2 diabetes, insulin resistance, glucose metabolism, and metabolic health
266 articoli
A large real-world study finds post-transplant diabetes requiring insulin marks a high-risk metabolic phenotype with far worse graft and patient outcomes.
A new framework redefines age-related insulin resistance as a systemic collapse of metabolic resilience spanning muscle, fat, brain, and more.
Un'analisi approfondita a livello molecolare sulla cinetica di formazione degli AGE, sulle isoforme di RAGE, sulle reti trascrizionali a valle e sugli interventi basati sull'evidenza — per chi vuole il quadro meccanicistico completo.
Vai oltre le basi ed esplora i meccanismi biochimici alla base della glicazione — dalla cascata della reazione di Maillard alla segnalazione RAGE e al cross-linking tissutale — per capire perché i AGE sono centrali nell'invecchiamento e nelle malattie metaboliche.
Scopri come le molecole di zucchero danneggiano silenziosamente le tue proteine e cellule nel tempo — e cosa puoi fare per rallentare questo subdolo processo di invecchiamento.
FDA approval of the first T1D delay drug nearly doubled islet autoantibody testing, but critical gaps remain in screening healthy children.
A new review links feline age-related obesity to SASP-driven chronic inflammation, offering translational insights for human metabolic disease.
The triple agonist retatrutide drives deep metabolic shifts beyond weight loss, improving key biomarkers of cardiovascular and insulin health.
Diabetes drugs like empagliflozin show surprising anti-aging effects — mimicking caloric restriction and reducing senescent cell burden.
Three new NIH-funded findings tackle metabolic aging, cardiovascular risk, and a surprising hormonal brake on brain tumors.
A rigorous MRI-based study finds that repeated hypoglycemia episodes leave brain glucose transport kinetics unchanged, challenging a leading hypothesis.
A novel endoluminal device implanted in the gut improved insulin sensitivity and weight control beyond what semaglutide achieved in a pig model.
