Heart Health
First Oral PCSK9 Inhibitor Cuts LDL Cholesterol by 80% in Phase 1 Trial
Laroprovstat, a once-daily pill, slashed LDL by 80% when combined with rosuvastatin — rivaling injectable PCSK9 inhibitors.
Articolo scientifico
16 mag 2026 0
Argomento
Malattie cardiache
Cardiovascular health, heart failure, atherosclerosis, and cardiac research
417 articoli
Heart Health
Vascular Aging Drives Whole-Body Decline and May Now Be Reversible
A landmark Circulation review reveals how aging blood vessels accelerate systemic decline — and outlines emerging therapies to stop it.
Articolo scientifico
14 mag 2026 0
Heart Health
AHA Updates Secondary Prevention Guidelines After Bypass Surgery
The American Heart Association's 2026 update outlines evidence-based strategies to slow disease progression and protect grafts after CABG.
Revisione
14 mag 2026 0
Heart Health
PRINCE Trial Authors Respond to Reader Debate on Remote Ischemic Preconditioning
The PRINCE trial investigators address scientific critiques of their landmark study on cardiac protection during noncardiac surgery.
Articolo scientifico
13 mag 2026 0
Heart Health
SGLT2 Inhibitors Deliver Far More Than Blood Sugar Control
A major review reveals how SGLT2 inhibitors protect the heart, kidneys, and metabolism through at least seven distinct biological mechanisms.
Articolo scientifico
12 mag 2026 0
Heart Health
SGLT2 Inhibitors Cut Death and Heart Failure Risk Even in Patients Over 80
Real-world study of 1,559 octogenarians finds SGLT2 inhibitors reduce all-cause death by 42% and heart failure rehospitalization by 31% with no increase in adverse events.
Articolo scientifico
12 mag 2026 0
Heart Health
Single-Pill Hypertension Therapy Remains Severely Underused Despite Proven Benefits
A decade of US data reveals persistent underuse of single-pill combination therapy for hypertension, despite its superiority for blood pressure control.
Articolo scientifico
12 mag 2026 0
Heart Health
Gaps in Post-Heart Attack Care Are Leaving Millions of Americans Unprotected
A major JACC study exposes how secondary prevention after myocardial infarction falls short across the U.S. population.
Articolo scientifico
12 mag 2026 0
Heart Health
Epicardial Fat Radiomics Could Transform Heart Failure Risk Prediction
AI-driven analysis of fat surrounding the heart may unlock a powerful new tool for predicting heart failure before symptoms emerge.
Articolo scientifico
12 mag 2026 0
Heart Health
Earlier Evolocumab Use Linked to Lower Arterial Aneurysm Risk in Major Trial
FOURIER and FOURIER-OLE data suggest that earlier initiation of the PCSK9 inhibitor evolocumab may reduce arterial aneurysm events.
Articolo scientifico
12 mag 2026 0
Heart Health
Low-Dose Digoxin Fails to Reduce Heart Failure Events in Major RCT
The DECISION trial finds low-dose digoxin did not significantly cut hospitalizations or cardiovascular death in 1,001 HFrEF/HFmrEF patients.
Articolo scientifico
12 mag 2026 0
Heart Health
miR-132 Inhibitor CDR132L Misses Primary Endpoint in Post-MI Heart Failure Trial
A phase 2 trial of the microRNA-132 inhibitor CDR132L showed safety but no significant improvement in cardiac remodeling after heart attack.
Articolo scientifico
12 mag 2026 0