Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
1634 articoli
First RCT evidence that semaglutide significantly reduces epigenetic age across multiple validated clocks in people with HIV-associated lipohypertrophy.
A 234-patient study shows lecanemab is feasible in specialty clinics, with ARIA occurring in 22% but severe events in only 1% of patients.
Scientists identify MRAP as a key molecular driver of thymic fat replacement, linking thymosin-α1 and FoxO1 signaling to immune aging.
Dendrobium officinale extract protects aging kidneys by activating antioxidant defenses through a key cellular signaling pathway.
A deubiquitinase stabilizes a key chaperone protein to activate protective autophagy and block iron-driven cell death in spinal discs.
Scientists discover PRDM16 declines in aged organs and its loss accelerates senescence; restoring it via GSTM1 may slow organ aging.
New research reveals omega-3s activate a receptor that curbs cellular senescence and fibrosis in kidneys, pointing to a clear biological mechanism.
Sunrise Air ditches clinic wires for a chin-worn sensor that tracks sleep apnea across multiple nights at home.
Forever Healthy's AI4L framework uses adversarial AI agents to verify every claim and citation in longevity evidence reviews.
Sam Altman-backed Retro Biosciences enters clinical trials with a drug targeting Alzheimer's protein clumps, aiming to add 10 healthy years to human life.
A multi-cohort study finds HLA-DRB1*15:01 significantly reduces longevity likelihood in northern European men, possibly via Alzheimer's and immune reactivity to LDL.
Scientists identify a glycolysis-serine axis controlled by PGK1 that governs podocyte aging, offering a new therapeutic target for chronic kidney disease.
