Stem cell therapies, regenerative medicine, tissue engineering, and cellular reprogramming
188 articoli
Xenotransplantation, 3D bioprinting, and stem cell therapies are converging to solve the global organ shortage crisis.
NIDCR researchers compared stromal cells from bone marrow, skin, spleen, and fat to identify which best regenerates bone and supports blood formation.
Scientists engineer high-PS procoagulant platelets that outperform thrombin and commercial hemostatic agents, even in antiplatelet-treated patients.
Harvard researchers identify a rare mesenchymal cell type that regenerates the thymus and boosts T cell immunity in aged animals.
Kyoto researchers built the first fully in vitro system that guides stem cells through every stage of human thymus development, producing functional T cells.
Computational protein design produces potent GPCR-targeting miniproteins for pain, cancer, obesity, and migraine with in vivo efficacy.
A phase 2b trial finds allogeneic MSC infusions improved 6-minute walk distance by 63 meters vs placebo at 9 months in frail older adults.
Cytosine base editing achieved 62–89% efficiency fixing a hyperinflammatory disease gene, but revealed distinct genotoxicity risks across cell types.
A special issue overview surveys three decades of peptide-based materials research, spotlighting applications from drug delivery to regenerative medicine.
A landmark clinical trial transplanted iPSC-derived dopamine neurons into Parkinson's patients using only tacrolimus — with no significant immune rejection.
Researchers 3D-printed silicone scaffolds seeded with human iPSC-derived spinal neural progenitor cells, transplanted them into transected rat spinal cords, and observed significant functional recovery at 12 weeks.
Padroneggia la scienza all'avanguardia dell'ingegneria degli esosomi, della farmacocinetica di rilascio e della traduzione clinica — dalle nanoparticelle caricate con CRISPR alla logica molecolare delle terapie rigenerative di nuova generazione.
