Stem Cell-Derived Hepatocytes Could Replace Liver Transplants
A translational review outlines how stem cell technologies may finally make hepatocyte-based liver therapies clinically viable.
Stem cell therapies, regenerative medicine, tissue engineering, and cellular reprogramming
188 articoli
A translational review outlines how stem cell technologies may finally make hepatocyte-based liver therapies clinically viable.
Human stem cells that migrate through 3µm channels spontaneously begin differentiating into bone cells — no chemical signals required.
A new review examines how umbilical cord-derived stem cells may repair dopaminergic neurons and slow Parkinson's progression beyond symptom relief.
Packaging mitochondria in erythrocyte-derived membranes dramatically improves delivery efficiency, pushing this experimental therapy closer to clinical reality.
A novel anti-swelling hydrogel loaded with dasatinib, quercetin, and nucleus pulposus exosomes clears senescent cells and restores disc integrity in rats and goats.
Scientists converted fibroblasts into functional osteoblasts using small molecules, then formed transplantable spheroids that repair bone defects without scaffolding.
Radiation triggers a Ca²⁺-NFATc1-Fis1 cascade that fragments mitochondria in bone marrow stem cells, halting bone repair — and silencing Fis1 reverses it.
A comprehensive 2025 review maps the mechanisms, sources, and clinical applications of mesenchymal stem cells and their derived exosomes across cardiovascular, neurological, autoimmune, and musculoskeletal diseases.
Approfondisci la riprogrammazione parziale, il rimodellamento della nicchia, i senolitici e le terapie cliniche all'avanguardia — il toolkit molecolare per invertire l'invecchiamento delle cellule staminali.
Scopri cosa sono le cellule staminali, i diversi tipi presenti nel tuo corpo e perché sono essenziali per mantenere i tuoi organi in salute con l'avanzare dell'età.
Padroneggia i bersagli molecolari più avanzati, i dati degli studi clinici e le strategie terapeutiche emergenti volte a invertire l'invecchiamento della ECM — dalle combinazioni senolatiche agli scaffold bioingegnerizzati, fino alla riprogrammazione epigenetica.
Embryonic brain precursor cells grafted into adult rat striatum successfully integrate and reduce motor deficits in a Parkinson's disease model.