MSC Therapy Shows Promise Despite Mixed Clinical Results
Review reveals safety of mesenchymal stem cell therapy but highlights efficacy challenges in clinical trials.
20 artigos
Review reveals safety of mesenchymal stem cell therapy but highlights efficacy challenges in clinical trials.
Comprehensive review reveals how MSCs repair tissues and modulate immunity across multiple diseases, offering new therapeutic pathways.
Uma revisão abrangente de 2025 revela como as MSCs reparam fígados danificados por meio de imunomodulação, ação antifibrótica e sinalização regenerativa.
Nova revisão consolida avanços na biologia das MSCs, aprovações clínicas e os obstáculos de padronização que ainda bloqueiam um sucesso terapêutico mais amplo.
Uma revisão de 2025 mapeia as evidências pré-clínicas e clínicas da terapia com células-tronco mesenquimais (MSC) no Alzheimer, detalhando mecanismos, limitações e perspectivas futuras.
A comprehensive 2025 review maps the mechanisms, sources, and clinical applications of mesenchymal stem cells and their derived exosomes across cardiovascular, neurological, autoimmune, and musculoskeletal diseases.
Ensaios de escalonamento de dose Fase Ia/Ib revelam que a terapia com MSC é segura na cirrose hepática descompensada, com doses mais altas produzindo efeitos mais intensos de reequilíbrio imunológico.
65-patient trial tested bone marrow stem cells injected directly into damaged heart muscle to restore function in chronic heart failure.
A combinação de transplante de células-tronco mesenquimais com exercício físico pode superar as principais limitações da terapia isolada para sarcopenia.
Scientists created modified stem cells that home to bone marrow, delivering targeted immune therapies while avoiding tumors entirely.
Researchers compared stem cells from arthritis patients versus healthy donors to assess regenerative therapy potential.
Adipose-derived stem cells combined with platelet-rich plasma evaluated for treating moderate to severe knee osteoarthritis over 2 years.
32-person trial compared bone marrow stem cells, platelet therapy, and hyaluronic acid for knee arthritis treatment over one year.
Tiny particles from stem cells could deliver therapeutic benefits without the risks of traditional cell-based treatments.
Combining nanoparticles with mesenchymal stem cells could finally overcome the poor survival and differentiation that limits cartilage regeneration.
Small trial tests autologous stem cells to regenerate damaged knee cartilage in osteoarthritis patients with promising safety profile.
Scientists explore safer alternatives to stem cell transplants using cellular secretions that may offer similar benefits.
Mesoblast licenses CAR technology to make its stem cell therapies smarter at finding inflamed tissue, targeting IBD and autoimmune disease.
A comprehensive review maps how mesenchymal stem cells and their exosomes combat Alzheimer's, atherosclerosis, osteoporosis, and ovarian failure.
Analysis of 449 clinical trials reveals mesenchymal stem cells are leading treatment for osteoarthritis and rheumatoid arthritis worldwide.