Cognitive performance, neuroplasticity, dementia prevention, and brain aging research
889 articoli
Cognitive reserve helps language performance early in svPPA, but accelerates decline once brain volume drops significantly.
A major Lancet review argues that optimizing current depression treatments may be more impactful than developing new ones.
A 4-protein panel in neuronal extracellular vesicles outperforms standard plasma tests in flagging early Alzheimer's brain changes.
New research maps a stress-signaling cascade linking p53 activation to brain inflammation and depression, with curcumin interrupting it.
A comprehensive review examines how marine-derived bioactives like omega-3s, astaxanthin, and polysaccharides may combat chronic neuroinflammation underlying major neurodegenerative diseases.
New research reveals how glucose availability directs brain cell proliferation via a metabolic-epigenetic axis, with implications for MS and brain repair.
Penn State researchers found abdominal contractions create pressure waves that gently rock the brain, boosting cerebrospinal fluid flow and waste clearance.
Raising Sox9 levels in aging astrocytes reduced amyloid plaque buildup and protected memory in mouse models with existing Alzheimer's symptoms.
A meta-analysis of 684,493 patients finds just 49% persist with anti-dementia drugs at 12 months, with major variation by drug type and study methodology.
A multi-cohort study finds that every 5 km closer to a lead-releasing facility is tied to measurably lower episodic memory scores.
Intracranial recordings reveal a low-dimensional subspace in human prefrontal cortex that selectively transmits context-relevant signals to motor cortex.
Esplora i meccanismi molecolari alla base della salute cerebrale nel corso della vita — dalle cascate di segnalazione BDNF-TrkB e la neurogenesi ippocampale adulta alla clearance glinfatica dell'amiloide, fino agli interventi all'avanguardia che includono senolitici, agonisti GLP-1 e stimolazione transcranica.
