Cognitive performance, neuroplasticity, dementia prevention, and brain aging research
889 articoli
Esplora ciò che accade realmente nel tuo cervello con l'avanzare dell'età — dal restringimento delle reti neuronali ai cambiamenti nei neurotrasmettitori — e scopri perché alcune persone mantengono una mente acuta ben oltre gli 80 anni.
Blocking the protein PTP1B boosted memory and cleared brain plaque in mice, with potential links to diabetes and obesity treatment.
Norwegian cohort study finds paternal valproate users have significantly higher epilepsy polygenic risk scores, suggesting genetic confounding may explain reported child neurodevelopmental risks.
A year-long sham-controlled trial finds active VNS meaningfully improves daily function and quality of life in patients who failed 4+ antidepressants.
A 2018 paper on antileukotriene therapy and tau phosphorylation in Alzheimer's mice has been retracted due to image fraud.
MethylCog, a 29-CpG blood test, indexes general cognitive ability and improves mild cognitive impairment detection beyond age and sex alone.
Neuropixels recordings reveal how laminar microcircuits generate interictal epileptiform discharges — and how to predict them 1 second in advance.
NfL biomarker levels in NORSE patients were 10-fold higher in CSF and 4-fold higher in serum than other seizure disorders, signaling massive neuroaxonal injury.
A 9-day intranasal insulin regimen restored working memory, recognition memory, and reduced neuroinflammation in mice engineered to mimic hippocampal aging.
Leading neurologists argue that amyloid aggregation dynamics may be distorting how we read clinical trial results for Alzheimer's immunotherapies.
A multi-omics subspace-merging algorithm identifies biologically distinct AD subtypes, pointing toward personalized treatment strategies.
A newly identified GABAergic pathway in mice lets the brain toggle between updated and previous memories — a key insight for memory disorders.
