Longevity & Aging

Cardiac Microtissues Show Promise for Heart Attack Recovery in Pig Study

Researchers developed 3D cardiac microtissues from human stem cells and tested them in pigs with heart attacks. These tissue clusters showed superior survival and integration compared to individual cells when transplanted into damaged heart muscle. The study used a triple immunosuppression protocol to prevent rejection and demonstrated that the microtissues could engraft onto native heart tissue four weeks after transplantation, suggesting potential for cardiac regenerative therapy.