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Autoimmune & Arthritis

Autoimmune disorders, rheumatoid arthritis, systemic inflammation, and immune dysregulation

305 articles

First Oral Peptide Drug for Autoimmune Diseases Shows Promise in Psoriasis Trials
Autoimmune & Arthritis

First Oral Peptide Drug for Autoimmune Diseases Shows Promise in Psoriasis Trials

Icotrokinra, a breakthrough oral peptide targeting IL-23, demonstrates significant skin clearance in psoriasis with sustained benefits through 52 weeks.

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8 avr. 2026 0
New Oral Psoriasis Drug Icotrokinra Outperforms Existing Treatment in Phase 3 Trials
Autoimmune & Arthritis

New Oral Psoriasis Drug Icotrokinra Outperforms Existing Treatment in Phase 3 Trials

Oral peptide targeting IL-23 receptor shows superior efficacy vs placebo and deucravacitinib in moderate-to-severe plaque psoriasis.

Article de recherche
8 avr. 2026 0
New Oral Drug Icotrokinra Shows Promise for Plaque Psoriasis Treatment
Autoimmune & Arthritis

New Oral Drug Icotrokinra Shows Promise for Plaque Psoriasis Treatment

Clinical trial results for oral icotrokinra in treating plaque psoriasis across adult and adolescent patients published in NEJM.

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7 avr. 2026 0
Atopic Dermatitis Has Distinct Immune Subtypes That Require Different Treatments
Autoimmune & Arthritis

Atopic Dermatitis Has Distinct Immune Subtypes That Require Different Treatments

New research reveals atopic dermatitis has multiple biological subtypes, each requiring personalized treatment approaches.

Article de recherche
5 avr. 2026 0
Silicosis Drug Target Discovered Through Mitochondrial Autophagy Pathway
Autoimmune & Arthritis

Silicosis Drug Target Discovered Through Mitochondrial Autophagy Pathway

New research identifies Lp-PLA2 enzyme as therapeutic target for deadly lung disease affecting millions of workers worldwide.

Article de recherche
5 avr. 2026 0
New Inhaled Drug Targets Airway Muscle to Treat Severe Asthma
Autoimmune & Arthritis

New Inhaled Drug Targets Airway Muscle to Treat Severe Asthma

Scientists develop potent α5β1 integrin inhibitor for inhalation therapy, offering new approach for severe asthma patients.

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5 avr. 2026 0
Spatial Mapping Reveals How Fibroblasts and Macrophages Drive Systemic Sclerosis
Autoimmune & Arthritis

Spatial Mapping Reveals How Fibroblasts and Macrophages Drive Systemic Sclerosis

New spatial multiomics study maps cellular interactions in systemic sclerosis, revealing fibroblast-macrophage dynamics.

Article de recherche
5 avr. 2026 0
IL-35 Blocks Neutrophil Traps to Reduce Smoking-Related Asthma Inflammation
Autoimmune & Arthritis

IL-35 Blocks Neutrophil Traps to Reduce Smoking-Related Asthma Inflammation

New research reveals how IL-35 therapy prevents neutrophil trap formation, offering hope for cigarette smoke-worsened asthma.

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5 avr. 2026 0
Calcineurin Inhibitors Show Promise for Autoimmune Diseases Despite Toxicity Risks
Autoimmune & Arthritis

Calcineurin Inhibitors Show Promise for Autoimmune Diseases Despite Toxicity Risks

Review examines immunosuppressive drugs like cyclosporine and tacrolimus, highlighting new applications and safety management strategies.

Article de recherche
4 avr. 2026 0
RNA Modification Protein IGF2BP3 Drives Joint Destruction in Rheumatoid Arthritis
Autoimmune & Arthritis

RNA Modification Protein IGF2BP3 Drives Joint Destruction in Rheumatoid Arthritis

New research reveals how IGF2BP3 protein promotes inflammation and tissue damage in rheumatoid arthritis through RNA modifications.

Article de recherche
4 avr. 2026 0
New Insights into Pemphigus Foliaceus Autoimmune Skin Disease
Autoimmune & Arthritis

New Insights into Pemphigus Foliaceus Autoimmune Skin Disease

Expert commentary on pemphigus foliaceus, a rare autoimmune blistering disease affecting skin health and immune function.

Article de recherche
4 avr. 2026 0
Italian MS Experts Reach Consensus on Personalized Multiple Sclerosis Treatment
Autoimmune & Arthritis

Italian MS Experts Reach Consensus on Personalized Multiple Sclerosis Treatment

Delphi study of 166 Italian neurologists establishes guidelines for individualized MS therapy based on patient needs and drug characteristics.

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3 avr. 2026 0
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