Brain Estrogen Loss Drives Memory Decline and Hippocampal Changes in Aging Females
New mouse study reveals why women face higher Alzheimer's risk — local brain estrogen deficiency triggers age-specific memory loss and ECM remodeling.
Cognitive performance, neuroplasticity, dementia prevention, and brain aging research
886 articles
New mouse study reveals why women face higher Alzheimer's risk — local brain estrogen deficiency triggers age-specific memory loss and ECM remodeling.
Microglia package healthy mitochondria into vesicles and deliver them to astrocytes, sharply reducing cognitive decline in tau-pathology mice.
Au plus profond de votre cerveau se trouve une minuscule région qui agit comme un centre de contrôle principal du vieillissement. Découvrez comment l'hypothalamus influence votre espérance de vie — et ce que vous pouvez faire pour le maintenir jeune.
New NIH research reveals the brain-cell signaling mechanism behind GLP-1 drug plateaus and a potential way to extend their effects.
New compounds targeting the cPLA2 enzyme may reduce Alzheimer's-linked brain inflammation, especially in high-risk APOE4 gene carriers.
A Phase 4 real-world study comparing extended-release methylphenidate formulations for ADHD was terminated before yielding conclusions.
New research reveals eye fixation duration is driven by memory encoding demands, not visual processing difficulty — reshaping how we understand attention.
Duke researchers restored healthy mitochondria to damaged nerve cells, cutting pain-related behaviors by 50% in mice with nerve pain.
Declining Menin in the hypothalamus drives inflammation and aging. Restoring it reversed decline; D-serine amino acid improved cognition in mice.
A Lancet review reveals stroke pathways fail to adequately address frailty, disability, and comorbidity — gaps with major consequences for older patients.
A new framework warns that AI tools used too early in medical education may prevent trainees from developing core clinical reasoning skills.
Researchers at University of Padova argue lesion network mapping has overlooked biological constraints that may undermine its clinical applications.