Cognitive performance, neuroplasticity, dementia prevention, and brain aging research
886 articles
27-Hydroxycholesterol triggers microglial senescence through iron dysregulation, and the iron chelator deferoxamine reverses the damage.
Transdermal alcohol monitors paired with machine learning can now detect drinking events with over 90% accuracy — a leap beyond flawed self-reports.
People with mild cognitive impairment recruit extra brain regions and show altered muscle control just to stay balanced while thinking.
Researchers matched fMRI patterns across mouse models and 1,976 humans to find autism splits into hypo- and hyperconnectivity subtypes with distinct biology.
New fMRI research from UNC Chapel Hill uncovers distinct neurological subtypes within ASD, potentially reshaping diagnosis and treatment.
Cannabis use is surging among adults over 65, but Stanford Medicine specialists say today's potent marijuana carries serious, underestimated health risks.
Applied Cognition tests a wearable device that tracks glymphatic function overnight, comparing it to MRI, EEG, and blood biomarkers.
A Phase 1/2 trial tests whether dexmedetomidine can enhance the brain's glymphatic system to clear amyloid and tau during sleep.
Specific AQP4 genetic variants alter glymphatic drainage efficiency, directly influencing motor symptom severity and progression in early Parkinson's disease.
New mouse study reveals aging causes region-specific neuroinflammation and perineuronal net accumulation linked to memory decline.
A landmark RCT tests whether hearing aids can protect brain health in 977 older adults over 3 years.
A landmark multicohort proteomics study reveals how APOE2 and APOE4 shape Alzheimer's risk through entirely distinct molecular mechanisms.
