Gut Bacteria Enzyme Boosts IBD Drug Response Through Lactate-Histone Pathway
A microbial enzyme from Bifidobacterium enhances anti-TNF therapy efficacy in IBD by reshaping immune regulation via histone lactylation.
Gut bacteria diversity, digestive health, probiotics, prebiotics, and the gut-brain axis
361 articles
A microbial enzyme from Bifidobacterium enhances anti-TNF therapy efficacy in IBD by reshaping immune regulation via histone lactylation.
A newly identified microRNA disrupts Paneth cell function in aging intestines, exposing older patients to life-threatening gut complications.
A specific gut bacterium produces deoxycholic acid that hijacks tumor immunity, offering new targets for breast cancer treatment.
A stem cell intestine model screened 3,500 compounds and flagged glycyrrhizin from black licorice as a top anti-inflammatory candidate for IBD.
A precision nutrition trial finds liver insulin resistance responds to dietary fat changes via gut microbiota shifts, while muscle IR does not.
A common gut microbe has evolved new oxygen tolerance in industrialized populations — and it may be reshaping your microbiome's spatial architecture.
A Princeton study finds maternal helminth exposure reshapes the microbiome to produce a metabolite that shields offspring from respiratory viruses.
A comprehensive review reveals how probiotics, bacteriophages, and predatory bacteria can restore oral microbial balance and prevent systemic disease.
A systematic review of 99 studies reveals how AI is transforming biomaterial design to combat drug-resistant oral infections.
A nationwide Korean birth cohort study finds maternal influenza infection in pregnancy may raise offspring risk of inflammatory bowel disease.
A comprehensive JAMA review covers HBV epidemiology, diagnosis, and antivirals that reduce hepatocellular carcinoma risk by ~50%.
First Mendelian randomization study finds 17 bacterial taxa causally influence white matter integrity, connectivity, and stroke risk.