Heart Health
SGLT2 Inhibitors Deliver Far More Than Blood Sugar Control
A major review reveals how SGLT2 inhibitors protect the heart, kidneys, and metabolism through at least seven distinct biological mechanisms.
Article de recherche
12 mai 2026 0
Sujet de recherche
Heart Health
Cardiovascular disease prevention, blood pressure, cholesterol, and heart function
617 articles
Heart Health
SGLT2 Inhibitors Cut Death and Heart Failure Risk Even in Patients Over 80
Real-world study of 1,559 octogenarians finds SGLT2 inhibitors reduce all-cause death by 42% and heart failure rehospitalization by 31% with no increase in adverse events.
Article de recherche
12 mai 2026 0
Heart Health
Single-Pill Hypertension Therapy Remains Severely Underused Despite Proven Benefits
A decade of US data reveals persistent underuse of single-pill combination therapy for hypertension, despite its superiority for blood pressure control.
Article de recherche
12 mai 2026 0
Heart Health
Gaps in Post-Heart Attack Care Are Leaving Millions of Americans Unprotected
A major JACC study exposes how secondary prevention after myocardial infarction falls short across the U.S. population.
Article de recherche
12 mai 2026 0
Heart Health
Epicardial Fat Radiomics Could Transform Heart Failure Risk Prediction
AI-driven analysis of fat surrounding the heart may unlock a powerful new tool for predicting heart failure before symptoms emerge.
Article de recherche
12 mai 2026 0
Heart Health
Earlier Evolocumab Use Linked to Lower Arterial Aneurysm Risk in Major Trial
FOURIER and FOURIER-OLE data suggest that earlier initiation of the PCSK9 inhibitor evolocumab may reduce arterial aneurysm events.
Article de recherche
12 mai 2026 0
Heart Health
Low-Dose Digoxin Fails to Reduce Heart Failure Events in Major RCT
The DECISION trial finds low-dose digoxin did not significantly cut hospitalizations or cardiovascular death in 1,001 HFrEF/HFmrEF patients.
Article de recherche
12 mai 2026 0
Heart Health
miR-132 Inhibitor CDR132L Misses Primary Endpoint in Post-MI Heart Failure Trial
A phase 2 trial of the microRNA-132 inhibitor CDR132L showed safety but no significant improvement in cardiac remodeling after heart attack.
Article de recherche
12 mai 2026 0
Heart Health
Senolytics, Gene Therapy and Lifestyle Can Slow Cardiovascular Aging
A 2025 review maps the molecular drivers of cardiac aging and evaluates drugs, CRISPR, stem cells, and lifestyle as countermeasures.
Article de recherche
11 mai 2026 0
Heart Health
Sacubitril/Valsartan Improves Exercise Capacity in HFpEF with Mitral Regurgitation
The PRAISE-MR trial finds sacubitril/valsartan significantly improves exercise hemodynamics and quality of life in a high-risk HFpEF phenotype.
Article de recherche
11 mai 2026 0
Heart Health
Digitalis Revisited: Old Heart Drug Cuts HF Hospitalizations by 25%
A JAMA meta-analysis of 9,000+ patients finds digitalis glycosides significantly reduce worsening heart failure events, reigniting interest in a centuries-old drug.
Article de recherche
11 mai 2026 0
Heart Health
How Chronic Inflammation Drives Heart Aging and What Can Stop It
A comprehensive review reveals how inflammaging—the fusion of aging and inflammation—fuels cardiovascular disease through senescence, mitochondrial dysfunction, and gut dysbiosis.
Article de recherche
10 mai 2026 0