Sujet

Maladie d'Alzheimer

Alzheimer's disease research, amyloid plaques, tau tangles, and cognitive decline

368 articles

Boosting Astrocyte Sox9 Clears Alzheimer's Plaques and Saves Memory in Mice
Brain Health

Boosting Astrocyte Sox9 Clears Alzheimer's Plaques and Saves Memory in Mice

Overexpressing Sox9 in brain support cells triggers plaque cleanup and protects cognition in Alzheimer's mouse models.

Article de recherche
26 avr. 2026 0
NR Supplementation Improves Brain Blood Flow and Cognition in PAD Patients
Brain Health

NR Supplementation Improves Brain Blood Flow and Cognition in PAD Patients

A 4-week pilot trial finds nicotinamide riboside boosts cerebrovascular response and cognitive performance in older adults with peripheral artery disease.

Article de recherche
24 avr. 2026 0
Dopamine Disruption in a Key Memory Hub May Drive Early Alzheimer's Symptoms
Brain Health

Dopamine Disruption in a Key Memory Hub May Drive Early Alzheimer's Symptoms

New research links early dopamine neuron dysfunction in the entorhinal cortex to memory loss in Alzheimer's — and L-DOPA reversed it in mice.

Article de recherche
24 avr. 2026 0
Cancer-Like Mutations in Brain Immune Cells May Fuel Alzheimer's Neuroinflammation
Brain Health

Cancer-Like Mutations in Brain Immune Cells May Fuel Alzheimer's Neuroinflammation

Somatic mutations found in cancer driver genes accumulate in Alzheimer's brain macrophages, potentially driving the neuroinflammation that accelerates disease.

Article de recherche
24 avr. 2026 0
Negative Physical and Social Environments Measurably Speed Up Brain Aging
Brain Health

Negative Physical and Social Environments Measurably Speed Up Brain Aging

New Nature Medicine research links harmful physical and social exposures to accelerated brain aging, with major implications for dementia prevention.

Article de recherche
23 avr. 2026 0
Astrocytes and Microglia Drive Alzheimer's Progression More Than Neurons
Brain Health

Astrocytes and Microglia Drive Alzheimer's Progression More Than Neurons

New single-nucleus and spatial transcriptomics data reveal glial cells—not just neurons—are central players in Alzheimer's disease pathology.

Article de recherche
22 avr. 2026 0
Rethinking How We Deliver Alzheimer Care at the System Level
Brain Health

Rethinking How We Deliver Alzheimer Care at the System Level

Researchers propose redesigning memory clinic services to match patient complexity with the right level of specialist oversight.

Article de recherche
22 avr. 2026 0
NIA Research Roundup Highlights Dementia Risk, Calorie Restriction and Alzheimer's Genes
Brain Health

NIA Research Roundup Highlights Dementia Risk, Calorie Restriction and Alzheimer's Genes

Recent NIA findings spotlight lifestyle factors cutting Alzheimer's risk by 60%, calorie restriction slowing aging, and a gene regulating plaque toxicity.

Communiqué de presse
21 avr. 2026 0
# Ingénierie Glymphatique : Cibles Moléculaires et Frontières Thérapeutiques
Brain Health
Premium

# Ingénierie Glymphatique : Cibles Moléculaires et Frontières Thérapeutiques

Maîtrisez l'architecture moléculaire des systèmes glymphatique et lymphatique méningé — des mécanismes de régulation par AQP4 à la thérapie VEGF-C — et explorez les interventions de pointe ciblant ces voies pour la prévention de la neurodégénérescence.

TutorielAvancé
20 avr. 2026 0
NIH Advances Aging and Alzheimer's Research With New Funding and Scientific Progress
Brain Health

NIH Advances Aging and Alzheimer's Research With New Funding and Scientific Progress

The National Institute on Aging outlines recent priorities in aging and Alzheimer's disease research, including budget planning and training initiatives.

Communiqué de presse
20 avr. 2026 0
Anti-Amyloid Alzheimer's Drugs Show Trivial Cognitive Benefit With Real Brain Bleed Risk
Brain Health

Anti-Amyloid Alzheimer's Drugs Show Trivial Cognitive Benefit With Real Brain Bleed Risk

A Cochrane meta-analysis of 17 RCTs finds amyloid-targeting antibodies offer minimal cognitive gains while significantly raising ARIA risk.

Synthèse
20 avr. 2026 0
Brain Surgery Survivors Face 18% Higher Death Rate and Lasting Cognitive Deficits a Decade Later
Brain Health

Brain Surgery Survivors Face 18% Higher Death Rate and Lasting Cognitive Deficits a Decade Later

A 10-year Swiss cohort study finds chronic subdural hematoma surgery patients suffer sustained excess mortality and significant cognitive and functional impairments.

Article de recherche
20 avr. 2026 0
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