Cancer Research
Why Cushing's Tumors Stop Responding to Temozolomide
New research reveals how corticotroph pituitary tumors develop resistance to temozolomide through clonal selection of high MGMT-expressing cells.
Article de recherche
19 mai 2026 0
Sujet
Cancer
Latest breakthroughs in cancer research, treatment, and prevention
602 articles
Cancer Research
Radiation Therapy Rivals Surgery for Early-Stage Liver Cancer in Largest Study Yet
A multinational study of 4,913 patients finds EBRT delivers survival outcomes comparable to surgery and ablation for early hepatocellular carcinoma.
Article de recherche
19 mai 2026 0
Cancer Research
Radiation to Metastases Cuts Cancer Progression Risk in Half in Phase II Trial
Adding targeted radiation to standard therapy reduced progression by 46% across multiple cancer types in the EXTEND trial.
Article de recherche
19 mai 2026 0
Cancer Research
Chemo-Free HER2+ Breast Cancer Treatment Achieves Excellent 5-Year Survival
A randomized trial shows hormone receptor-positive/HER2+ early breast cancer patients had 100% 5-year overall survival with endocrine therapy plus dual HER2 blockade.
Article de recherche
19 mai 2026 0
Cancer Research
New Macrocyclic Peptides Selectively Kill Chemotherapy-Resistant Lung Cancer Cells
Orally bioavailable cyclin A/B RxL inhibitors exploit a cell-cycle vulnerability in small-cell lung cancer and other G1-S-checkpoint-deficient tumors.
Article de recherche
18 mai 2026 0
Cancer Research
Cancer's Growth Protein MYC Found to Secretly Repair Chemo-Damaged DNA
MYC protein doesn't just fuel tumor growth — it also repairs DNA damage from chemotherapy, revealing a key resistance mechanism.
Communiqué de presse
17 mai 2026 0
Cancer Research
Phase I Trial Tests Ipilimumab Added to Chemoradiation for Advanced Cervical Cancer
NCI-sponsored trial evaluates safety and optimal dosing of immune checkpoint blockade following standard chemoradiation in locally advanced cervical cancer.
Essai clinique
17 mai 2026 0
Cancer Research
Dual Checkpoint Blockade Plus FOLFOX Chemo Tested in Metastatic Colorectal Cancer
A Phase 1/2 trial tests whether combining durvalumab, tremelimumab, and FOLFOX chemotherapy can safely boost immune response in mCRC.
Essai clinique
17 mai 2026 0
Cancer Research
Leukemic Stem Cells Make Their Own Ketones to Dodge Cell Death
AML stem cells produce BHB via autonomous ketogenesis to block ferroptosis, revealing a targetable metabolic vulnerability in leukemia.
Article de recherche
17 mai 2026 0
Cancer Research
New Immune Checkpoint Found as Neutrophils Sabotage Cancer-Fighting T Cells
Scientists identify CD300ld as a key mechanism by which tumor-infiltrating neutrophils silence CD8+ T cells, opening a new immunotherapy target.
Article de recherche
17 mai 2026 0
Cancer Research
Combined ctDNA and PSA Testing Predicts Survival in Metastatic Prostate Cancer
A prospective cohort study shows combining ctDNA with PSA levels dramatically improves survival prediction in high-volume metastatic prostate cancer patients.
Article de recherche
17 mai 2026 0
Cancer Research
Online Mindfulness Program Shows Promise for Gynecological Cancer Patients
A Swiss feasibility trial tests digital mindfulness-based cancer recovery, tracking psychosocial outcomes, medication use, and biological markers.
Essai clinique
16 mai 2026 0