20 artigos
A comprehensive review reveals methylene blue's expanding role from toxicology emergencies to perioperative care, neurology, and oncology.
Current labeling urges nursing mothers to pause breastfeeding for 8 days after methylene blue, but the underlying evidence is thin.
FDA-approved methylene blue reduced delirium-like behavior in surgical mice by suppressing neuroinflammation and repairing the blood-brain barrier.
A meta-analysis of 15 studies finds methylene blue therapy significantly reduces mortality in ICU septic shock patients, with hemodynamic benefits.
A 2025 review examines how methylene blue's nitric oxide inhibition can restore vascular tone in septic and vasoplegic shock patients.
A primate study shows methylene blue treats fatal cerebral malaria and uncovers neutrophil-linked genes as diagnostic biomarkers.
Um ECR multicêntrico com 566 pacientes sendo lançado em toda a China para determinar se o azul de metileno precoce reduz a mortalidade em 28 dias no choque séptico dependente de vasopressores em altas doses.
Um estudo com 200 pacientes constata que o uso precoce de azul de metileno no choque vasoplégico pós-cirurgia de bypass reduz pela metade o tempo de internação na UTI e diminui as taxas de insuficiência renal.
Um relato de caso do Surrey and Sussex NHS Trust destaca os riscos da extravasação de azul de metileno na mão e no antebraço durante cirurgia de paratireoide.
A comprehensive review reveals how advanced oxidation processes can efficiently degrade methylene blue, a persistent textile pollutant threatening human health.
Adding methylene blue to ropivacaine in a serratus anterior plane block significantly prolongs pain relief up to 72 hours post-op.
A comprehensive review reveals how plant-derived nanomaterials catalytically neutralize toxic dyes and nitrophenols from industrial wastewater with remarkable efficiency.
New research shows blue light triggers harmful changes in retinal cells by disrupting mitochondrial function, offering targets for AMD prevention.
MethylCog, a 29-CpG blood test, indexes general cognitive ability and improves mild cognitive impairment detection beyond age and sex alone.
A 4-week-old infant developed severe methemoglobinemia after EMLA cream was applied for circumcision, highlighting hidden dangers of topical anesthetics.
Uma metanálise Cochrane de 17 ECRs conclui que a TURBT com luz azul reduz a recorrência e a progressão do câncer de bexiga, especialmente em pacientes de risco intermediário e alto.
Morning blue light exposure stabilized attention during cognitive tasks, reducing moment-to-moment mental variability in young adults.
A 303-tumor study shows DNA methylation arrays can classify neuroblastoma into prognostically meaningful subgroups, potentially replacing multiple genomic tests.
A cianidina-3-O-glicosídeo, uma antocianina natural, reduz as células T reguladoras (Tregs) imunossupressoras e retarda o crescimento do mieloma múltiplo em camundongos e estudos celulares.
Delphinidin, a natural anthocyanin, prevented microglial senescence via AMPK/SIRT1 signaling, reducing amyloid plaques and restoring cognition in AD mice.
